Results 131 to 140 of about 1,768,787 (301)

Living Standards and Mortality since the Middle Ages [PDF]

Existing studies find little connection between living standards and mortality in England, but go back only to the sixteenth century. Using new data on inheritances, we extend estimates of mortality back to the mid-thirteenth century and find, by ...
Cormac Ó Gráda, Morgan Kelly
core  

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Africa’s Transitions to the Middle Ages

Medieval Worlds, 2022
Paolo Tedesco
doaj   +1 more source

Some remarks on the arms production in medieval Poland : 13th-15th centuries

Fasciculi Archaeologiae Historicae, 1992
...
Jan Szymczak
doaj  

Temple symbolism in the architecture of middle ages Europe [PDF]

, 2019
Висвітлено такі акценти: християнські символи існують і для приховування істини, і для її виявлення, пізнання; пізнання вищої істини можливе лише на основі розкодування символічних образів, що втілені у середньовічному мистецтві та архітектурі, а ...
Михалевич, Віктор Вадимович
core  

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

What's "Middle" About the Middle Ages? [PDF]

A medieval historian explains why the Dark Ages weren't dark at all and why they are fun to ...
Brown, Warren C.
core  

Некаторыя аспекты тэхналогіі вырабу познесярэдневечнага посуду Беларусі [PDF]

, 2015
У святле стварэння нацыянальнага каларыту аграсядзіб паўстае пытанне адраджэнне традыцыйных начынняў для страваў, што стане важным элементам надання мясцовага каларыту іх інтэр’еру. Гэта патрабуе вывучэння пытанняў тэхналогіі вытворчасці посуду.
Здановіч, Ніна Іванаўна
core