Results 131 to 140 of about 416,313 (253)

Ibn al-Jazzar (al-Gizar): A Renowned Tunisian Physician in General Medicine, Women's Diseases, and Pediatrics During the Middle Ages. [PDF]

Cureus
Zridi S, Dghim I, Jellad A.
europepmc   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Faltering mortality improvements at young-middle ages in high-income English-speaking countries. [PDF]

Int J Epidemiol
Timonin S, Leon DA, Banks E, Adair T, Canudas-Romo V.   +4 more
europepmc   +1 more source

Between belief and fear - Reinterpreting prone burials during the Middle Ages and early modern period in German-speaking Europe. [PDF]

PLoS One, 2020
Alterauge A, Meier T, Jungklaus B, Milella M, Lösch S.   +4 more
europepmc   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Treating with minerals in the Middle Ages: the rare substance mūmiyā' (pitch-asphalt) and its medicinal uses in Byzantium. [PDF]

Med Hist
Bouras-Vallianatos P, Käs F.
europepmc   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

A randomized controlled clinical study of acupuncture therapy for Seborrheic alopecia in young and middle ages: Study protocol clinical trial (SPIRIT compliant). [PDF]

Medicine (Baltimore), 2020
Chen Q, Tao Y, Wang L, Zhang J, Sun B, Yang X.   +5 more
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Introduction, spread and selective breeding of crops: new archaeobotanical data from southern Italy in the early Middle Ages. [PDF]

Veg Hist Archaeobot
Fiorentino G, Grasso AM, Primavera M.
europepmc   +1 more source