Results 231 to 240 of about 32,046 (262)

Bioorthogonal Fluorogenic Reporters for Noninvasive Imaging and Urinalysis of Immunotherapeutic Response in Renal Cell Carcinoma

Advanced Science, EarlyView.
This study reported renal‐clearable bio‐orthogonal near‐infrared fluorogenic probes (BGRs) that specifically imaging and urinalysis of granzyme B for dynamic evaluation of RCC immunotherapy. BGRs not only differentiate immunotherapeutic responses in orthotopic RCC mice, but also enable sensitive optical urinalysis of granzyme B in clinical specimens ...
Xingyue Yang, Baoshuai Liang, Liangmin Fu, Weiliang Deng, Yuyan Jiang, Weiping Xu, Jinwei Chen, Ya Zhou, Ke Wu, Jiaguo Huang   +9 more
wiley   +1 more source

Lactation is Associated with Accelerated Postpartum Pelvic Floor Muscle Recovery in a Pregnant Simulated Birth Injury Model

Advanced Science, EarlyView.
ABSTRACT Healthy pelvic floor muscles (PFMs) are essential for proper pelvic floor function. The biggest risk factor for PFM dysfunction is injury sustained during vaginal childbirth, yet the factors that facilitate or impair PFM recovery from birth injury remain unknown.
Bianca L. Peña, Khushi M. Diwakar, Hillary K. Tran, Selena Cao, Celeste E. Lintz, Laila N. Hayes, Marianna Alperin, Karen L. Christman   +7 more
wiley   +1 more source

Feeder-free yet still naïve: improved method for capturing human pluripotent stem cells. [PDF]

EMBO J
Yagi M, Hochedlinger K.
europepmc   +1 more source

Materials‐Guided Gene‐Ionizable Lipid Nanoparticles to Reverse Iron‐Associated Immune Resistance in Renal Cancer

Advanced Science, EarlyView.
ABSTRACT Iron overload is a common metabolic disturbance in cancer and contributes to poor outcomes in renal cell carcinoma (RCC), yet its effects on the tumour immune microenvironment remain unclear. Here we identify a previously unrecognized immunosuppressive axis in which iron overload downregulates the palmitoyltransferase ZDHHC12 in CD8+ T cells ...
Xin Jin, Yulong Hong, Chengliang Yin, Wanyang Guo, Yaxuan Wang, Ruijiang Zeng, Ruilin Liu, Zexian Ding, Xinlin Liu, Shangqing Ren, Qiyang Liang, Yaohui Wang, Xu Zhang, João Conde, Yuan Li, Xin Ma, Liangyou Gu   +16 more
wiley   +1 more source

Maternal awareness and practices regarding vitamin D and their impact on health outcomes in children under five years in Egypt. [PDF]

Sci Rep
Saleh SE, Hendy A, Ibrahim RK, Badr EA.
europepmc   +1 more source

Lone black holes promise fresh insights into the fates of massive stars. [PDF]

Proc Natl Acad Sci U S A
Croswell K.
europepmc   +1 more source

Discovery of functional compounds from dimorphic edible <i>Ophiocordyceps sinensis</i> fungus in host haemolymph. [PDF]

Synth Syst Biotechnol
Sun T, Yang Y, Xie J, Rao Z, Han R, Cao L.   +5 more
europepmc   +1 more source

Simulations of multi-phase gas in and around galaxies. [PDF]

Living Rev Comput Astrophys
Gronke M, E Schneider E.
europepmc   +1 more source

Elucidation of key aroma-active compounds and sensory profiles in raw and thermally sterilized milks: Perspective from molecular sensory science. [PDF]

Food Chem X
Xu K, Han H, Wang X, Zhang X, Yang X, Lu X, Han Z, Wang S, Wang Y, Wang B.   +9 more
europepmc   +1 more source

Progressive multifocal leukoencephalopathy - a diagnostic guide for the clinical neurologist. [PDF]

Front Neurol
Jia DT.
europepmc   +1 more source