Results 91 to 100 of about 137,617,223 (311)
RNA‐related functions of BRCA2 in transcription, replication, and genome stability
FEBS Letters, EarlyView.Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda +2 more
wiley +1 more source
Genetic structure and historic demography of endangered unarmoured threespine stickleback at southern latitudes signals a potential new management approach. [PDF]
Mol Ecol, 2022 Turba R +9 more
europepmc +1 more source
New Jersey Floodplain News: Issue 5
, 2009 New Jersey Association for Floodplain Management (NJAFM) is dedicated to reducing loss of life and property damage resulting from floods and promoting sound floodplain management at all levels of government. This issue of NJAFM's newsletter features the
core +1 more source
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
FEBS Letters, EarlyView.The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
The comprehensive hazardous waste management plan
, 1987 The NJ Department of Environmental Protection is pleased to present its Comprehensive Hazardous Waste Management Plan for the next five years. This Plan will launch a bold new direction for how hazardous wastes are managed in the future.
core
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
A NEW APPROACH TO THE ASSESSMENT OF EFFECTIVE MANAGEMENT OF GAS SUPPLY DIVERSIFICATION
Baltic Journal of Economic Studies, 2017 The purpose of the paper is to study the current state and trends in the development of the basic indicators of the EU gas sector, to generalize the theoretical and methodological approaches to calculating the gas diversification factor, assess and ...
Oleh Dzoba +2 more
doaj
The standard for organizational project management (OPM)
, 2018 The Standard for Organizational Project Management (OPM) provides a framework and integrated approach using portfolio, program, and project management to deliver organizational strategy for better performance, better results, and a sustainable ...
Project Management Institute
core
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
An indigenous approach to the Living Standards Framework
, 2019 The move by the Treasury to explore ways to view national wellbeing as representing more than the traditional Gross Domestic Product (GDP)-based measures is a welcome shift.
The Treasury - New Zealand Government
core