Results 71 to 80 of about 132,110,753 (310)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
New Jersey ... unknown, known, should be known and will be known:
, 2003 An overview of New Jersey interspersed with the author's reminiscences of her life in the ...
Johns, Beatrice
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Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Current Research in BiotechnologyObesity is a complex, multifactorial disease characterized by excessive body fat accumulation, which negatively impacts health. Its increasing prevalence has led to a global epidemic, emphasizing the urgent need for innovative and effective treatment ...
Esmail Karami +3 more
doaj +1 more source
New Jersey Floodplain News, Issue 3
, 2008 New Jersey Floodplain News, which is published bi-annually, is the newsletter for the New Jersey Association for Floodplain Management (NJAFM). The newsletter provides information on flooding, while advocating sound floodplain management in New Jersey ...
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The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Sentinel Lymph Node Biopsy : A new approach in the management of head and neck cancers
Sultan Qaboos University Medical Journal, 2017 Cervical lymph node metastasis affects the prognosis and overall survival rate of and therapeutic planning for patients with head and neck squamous cell carcinomas (HNSCCs).
Deepti Sharma +2 more
doaj +1 more source
An indigenous approach to the Living Standards Framework
, 2019 The move by the Treasury to explore ways to view national wellbeing as representing more than the traditional Gross Domestic Product (GDP)-based measures is a welcome shift.
The Treasury - New Zealand Government
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New Jersey Floodplain News: Issue 5
, 2009 New Jersey Association for Floodplain Management (NJAFM) is dedicated to reducing loss of life and property damage resulting from floods and promoting sound floodplain management at all levels of government. This issue of NJAFM's newsletter features the
core +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source