Results 81 to 90 of about 132,101,555 (310)

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Targeting the UCP1-dependent thermogenesis pathway with CRISPR/Cas9: a new approach to obesity management

open access: yesCurrent Research in Biotechnology
Obesity is a complex, multifactorial disease characterized by excessive body fat accumulation, which negatively impacts health. Its increasing prevalence has led to a global epidemic, emphasizing the urgent need for innovative and effective treatment ...
Esmail Karami   +3 more
doaj   +1 more source

New Jersey ... unknown, known, should be known and will be known:

open access: yes, 2003
An overview of New Jersey interspersed with the author's reminiscences of her life in the ...
Johns, Beatrice
core   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

New Jersey Floodplain News, Issue 3

open access: yes, 2008
New Jersey Floodplain News, which is published bi-annually, is the newsletter for the New Jersey Association for Floodplain Management (NJAFM). The newsletter provides information on flooding, while advocating sound floodplain management in New Jersey ...

core   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Sentinel Lymph Node Biopsy : A new approach in the management of head and neck cancers

open access: yesSultan Qaboos University Medical Journal, 2017
Cervical lymph node metastasis affects the prognosis and overall survival rate of and therapeutic planning for patients with head and neck squamous cell carcinomas (HNSCCs).
Deepti Sharma   +2 more
doaj   +1 more source

An indigenous approach to the Living Standards Framework

open access: yes, 2019
The move by the Treasury to explore ways to view national wellbeing as representing more than the traditional Gross Domestic Product (GDP)-based measures is a welcome shift.
The Treasury - New Zealand Government
core  

New Jersey Floodplain News: Issue 5

open access: yes, 2009
New Jersey Association for Floodplain Management (NJAFM) is dedicated to reducing loss of life and property damage resulting from floods and promoting sound floodplain management at all levels of government. This issue of NJAFM's newsletter features the

core   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

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