Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Correction: Family support after a family member's suicide: A qualitative exploration. [PDF]
PLOS One Staff.
europepmc +1 more source
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Toxic buffers used in microbial sample preservation for SEM can be replaced by PBS [PDF]
Banas Indra +3 more
doaj +1 more source
Expression of Concern: A study on the temperature profile of bifurcation tunnel fire under natural ventilation. [PDF]
PLOS One Editors.
europepmc +1 more source
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Expression of Concern: Evaluating the compressive strength of glass powder-based cement mortar subjected to the acidic environment using testing and modeling approaches. [PDF]
PLOS One Editors.
europepmc +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Visualizing microbial interactions and CRISPR-Cas interference using FISH applied to environmental archaeal biofilms [PDF]
Banas Indra +3 more
doaj +1 more source
Correction: Retraction: Unleashing the role of e-word of mouth on purchase intention in select Facebook fan pages of smart phone users. [PDF]
PLOS One Editors.
europepmc +1 more source

