Results 131 to 140 of about 139,445,430 (292)

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Volume-corrected renal arterial pulsatility index in IVF-ET fetuses and naturally conceived fetuses: establishing reference ranges and correlation with gestational age

open access: yesEuropean Journal of Medical Research
Introduction The effect of in vitro fertilization-embryo transfer (IVF-ET) on fetal renal development remains insufficiently characterized. This study investigated the volume-corrected renal arterial pulsatility index (vcRAPI) in IVF-ET and naturally ...
Yanhua Cai, Xuanzhi Liu, Huaiqi Yao
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Interactive networks of donors and recipients of the TetM gene and its evolutionary dynamics across the bacterial domain

open access: yesScientific Reports
Identifying primary donors and recipients of the tetM gene is crucial for gaining a deeper understanding of the dynamics underlying the dissemination of resistance to tetracyclines in natural bacterial populations, including those of human and animal ...
Rusudan Tsiklauri   +2 more
doaj   +1 more source

The One That Got Away

open access: yes, 2014
Nominated for the Crashaw Prize, The One That Got Away is the debut collection from former Listowel prizewinner, Graham Allen. Professor of English at University College Cork, Graham Allen's poetry has appeared Southword, Other Poetry, The Stinging ...
Allen, Graham
core  

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

What Halo? We Never Had One!

open access: yes, 1968
The John Peter Zenger Award for Freedom of the Press and the People's Right to Know, 1968 / What Halo? We Never Had One! An Address by Wes Gallagher, General Manager, The Associated PressIncludes list of previous Zenger Award winners and foreword by ...
Gallagher, Wes
core   +2 more sources

Contested cultures of care: research with and for the plus one community on the plus one experience - evaluation report [PDF]

open access: yes, 2019
Benaton, Tonimarie   +6 more
core  

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

One for the Road (5 photos)

open access: yes, 1989
Presented as a part of "Beckett/Pinter," a collection of one-act plays performed together during the 1989-1990 ...
Pinter, Harold, 1930-2008
core  

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