Results 31 to 40 of about 12,004,822 (199)

Analyzing Characteristics of Experts in the Context of Stoichiometric Problem-Solving

open access: yesEducation Sciences, 2019
To gauge the variability in expert problem-solving strategies for stoichiometry problems, a set of experts in different career tracks were studied with the cohort including 17 graduate students in chemistry, three college chemistry instructors, and seven
Ozcan Gulacar   +5 more
doaj   +1 more source

Serological Benefit of SARS‐CoV‐2 Vaccination Relative to Infection in Children With Acute Lymphoblastic Leukemia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with acute lymphoblastic leukemia (ALL) are at risk of severe outcomes from SARS‐CoV‐2 (SCV2). In the post‐pandemic context, where most children have been infected with SCV2, there are limited data on whether vaccination remains beneficial in children with ALL.
Janna R. Shapiro   +11 more
wiley   +1 more source

Deep Sequencing of FLT3‐ITD Enables Response Evaluation and Post‐Treatment Monitoring in Childhood AML: An Exploratory Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm   +11 more
wiley   +1 more source

Claudin‐6 Protein Expression in Atypical Teratoid/Rhabdoid Tumors Is Strongly Enriched in the Molecular Subgroup AT/RT‐TYR

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Claudin‐6 has emerged as a promising immunotherapeutic target, yet protein‐level data in atypical teratoid/rhabdoid tumors (AT/RTs) have been inconsistent. We analyzed 36 well‐characterized AT/RT samples and found membranous claudin‐6 protein expression in 58% of cases, with striking enrichment in the molecular subgroup AT/RT‐TYR (100%) and ...
Victoria E. Fincke   +4 more
wiley   +1 more source

Perceptions, attitudes, practices, and factors associated with COVID-19 vaccination among travelers in the Democratic Republic of the Congo

open access: yesTropical Diseases, Travel Medicine and Vaccines
Background Vaccination against COVID-19 has been the primary public health measure implemented to limit the spread of the disease. However, there is still considerable scope for improvement in vaccine coverage, particularly in sub-Saharan African ...
Harry César Kayembe   +16 more
doaj   +1 more source

Ecologically expanding the One Health framework to unify the microbiome sciences

open access: yesmBio
The One Health framework, traditionally focused on microbial threats, needs a bold expansion to include the full breadth of microbial diversity—from pathogenic to beneficial—within its ecological and evolutionary context.
Nichole Ginnan   +7 more
doaj   +1 more source

Cytokine profiles in early rejection following OKT3 treatment in liver transplant patients

open access: yesMediators of Inflammation, 2000
OKT3, a murine monoclonal antibody specific to the human CD3 complex, induces immunosuppression by depletion of T cells. Administration of OKT3 results in significant release of proinflammatory cytokines, such as TNFα and IL1β.
Sasan Roayaie   +6 more
doaj   +1 more source

Time Toxicity in Wilms Tumor: Quantifying the Burden of Healthcare Interaction in the First Year After Diagnosis

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Wilms tumor (WT) treatment imposes a significant time burden on patients and their families. Time toxicity is a patient‐centered metric that quantifies the burden of healthcare interaction. We sought to define time toxicity in the first year after diagnosis of WT and hypothesized that it would increase as tumor stage and treatment ...
Caleb Q. Ashbrook   +6 more
wiley   +1 more source

Parental Occupation and the Gender Math Gap: Examining the Social Reproduction of Academic Advantage among Elementary and Middle School Students

open access: yesSocial Sciences, 2017
Math proficiency is considered a critical subject for entry into most science, technology, engineering, and math (STEM) occupations. This study examines the relationship between parental occupation and gender differences in students’ math performance ...
Monica Bowden   +3 more
doaj   +1 more source

Regulation of IDO2 by the Aryl Hydrocarbon Receptor (AhR) in Breast Cancer

open access: yesCells, 2023
Indoleamine 2,3-dioxygenase 2 (IDO2) is a tryptophan-catabolizing enzyme and a homolog of IDO1 with a distinct expression pattern compared with IDO1. In dendritic cells (DCs), IDO activity and the resulting changes in tryptophan level regulate T-cell ...
Sarah Y. Kado   +9 more
doaj   +1 more source

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