Results 121 to 130 of about 10,385,733 (292)

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Corrigendum: Type 2 diabetes increases risk of unfavorable survival outcome for postoperative ischemic stroke in patients who underwent non-cardiac surgery: A retrospective cohort study

Frontiers in Aging Neuroscience, 2023
Faqiang Zhang, Faqiang Zhang, Yulong Ma, Yao Yu, Miao Sun, Hao Li, Jingsheng Lou, Jiangbei Cao, Yanhong Liu, Mu Niu, Long Wang, Weidong Mi, Weidong Mi   +12 more
doaj   +1 more source

MGP: Multi-Stage Grouped Probe Detection for Fault Localization in Vehicle-to-Ground Communication Networks

IEEE Open Journal of Vehicular Technology
The Vehicle-to-Ground (V2G) emergency communication network is a dedicated network established to respond to emergencies, such as natural disasters and traffic accidents, and it plays a crucial role in ensuring the safe and smooth operation of vehicles ...
Wenxiao Wang, Ping Dong, Yuyang Zhang, Wenxuan Qiao, Xiaoya Zhang, Chengxiao Yu, Hongke Zhang   +6 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Effect of remimazolam on inflammatory reaction after ureteroscopic lithotripsy: a randomised controlled trial

BMC Anesthesiology
Background Ureteral stone lithotripsy may cause a strong inflammatory response and may be associated with patient outcomes. In clinical practice, remimazolam has been widely used for induction and maintenance of general anesthesia.
Xiaoxia Gu, Jianhang Mo, Dianqing Cao, Ping Pang, Yan Lu, Ruizhao Shao, Kui Hu, Jingjing Wang, Guangbin Liang   +8 more
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

The sequence operation in production flows [PDF]

The sequence operation in production flows appears in the usual practice for the installations waiting time decreasing when a lot of pieces use the same technology line in the same direction.algorithm, permutation ...
Catalin Angelo Ioan
core   +1 more source

Multiindistinguishability Operators

International Journal of Approximate Reasoning
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Boixader Ibáñez, Dionís, Recasens Ferrés, Jorge   +1 more
openaire   +3 more sources

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

In Lower‐Grade Gliomas, the SPARC Family Exacerbates Prognosis by Influencing Immunity, Stemness, and Metabolism

Cancer Reports
Background Involvement of the SPARC stromal protein family in crucial biological regulatory mechanisms is well‐documented. But understanding the consequences of imbalanced SPARC protein activity in lower‐grade glioma (LGG) is still emerging.
Qiaoying Peng, Wenxia Zhou, Ying Chen, Yong Cai   +3 more
doaj   +1 more source