Results 71 to 80 of about 2,643,694 (314)

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

A Survey on Operator Monotonicity, Operator Convexity, and Operator Means [PDF]

open access: yesInternational Journal of Analysis, 2015
This paper is an expository devoted to an important class of real-valued functions introduced by Löwner, namely, operator monotone functions. This concept is closely related to operator convex/concave functions. Various characterizations for such functions are given from the viewpoint of differential analysis in terms of matrix of divided differences ...
openaire   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

An evaluation of the operation and impact of The Ark Children's Council [Executive Summary] [PDF]

open access: yes, 2019
This research is intended to create an understanding of how The Ark's practice of child consultation could be developed, enhanced and further embedded into the organisation's structures alongside the objectives of The Ark Strategy: 2017-2020.In 2018 ...
Cummins-McNamara, Annie   +2 more
core  

Chemical Processing Department Monthly Report: 1963-01

open access: yes, 1963
This report, for January, 1963 from the Chemical Processing Department at HAPO, discusses the following: Production operation; Purex and Redox operation; finished products operation; financial operations; facilities engineering; research employee ...
Hanford Atomic Products Operation. Chemical Processing Department.
core   +1 more source

Effectiveness Verification of Train Real-time Positioning Function Based on Speed Measuring Radar and Electronic Map under TACS

open access: yesChengshi guidao jiaotong yanjiu
Objective At present, CBTC (communication based train control) precise train positioning technology is prone to high cost of engineering construction and reconstruction, positioning errors and etc. Therefore, it is necessary to upgrade the existing train
ZHANG Zhiyi
doaj   +1 more source

On Integral Operators with Operator-Valued Kernels [PDF]

open access: yesJournal of Inequalities and Applications, 2010
Here Lq-Lp boundedness of integral operator with operator-valued kernels is studied and the main result is applied to convolution operators. Using these results Besov space regularity for Fourier multiplier operator is established.
openaire   +4 more sources

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Records of the Operation Drake

open access: yes, 1978
This record was harvested from a previous catalogue system and will be withdrawn in 2025. Information in this record may be superseded or incomplete.
Operation Drake
core  

Chemical Processing Department Monthly Report: 1963-09

open access: yes, 1963
This report, from the Chemical Processing Department at HAPO for September 1963, discusses the following: Production operation; Purex and Redox operation; Finished products operation; maintenance; Financial operations, facilities engineering; research ...
Hanford Atomic Products Operation. Chemical Processing Department.
core   +1 more source

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