Results 41 to 50 of about 78,203 (310)

Natural Products Inspired Scaffold Diversification Leads to Unnatural Molecular Warhead and Covalent Strategy to Modulating Protein Function through Electrophilic Bromine Transfer

Advanced Science, EarlyView.
We report a new thiolate‐reactive α,α‐gem‐dibromo lactam warhead that activates transcription factor Nrf2 and demonstrates anti‐inflammatory activities, which have implications in cancer, neurodegeneration, and cardiovascular diseases. RNA‐seq illuminated detailed transcriptional profiles, and chemical reactions with cysteine‐containing compounds ...
Beau R. Brummel, Sofia Kokkaliari, Qiwen Gao, Jinjing Chen, Larissa Costa de Almeida, Srinivasarao Tenneti, Derek A. Leas, Eli Levit, Lewis S. Alexander, Khalil A. Abboud, Pingrong Wei, Michael D. Cameron, James R. Rocca, Ranjala Ratnayake, Donna D. Zhang, Hendrik Luesch, Robert W. Huigens III   +16 more
wiley   +1 more source

Otakar Zich: Aesthetic and Artistic Evaluation, Parts 2 & 3

Estetika, 2010
In this important article, first published in 1917, the Czech aesthetician, musicologist, and composer Otakar Zich (1879–1934) distinguishes between two kinds of evaluation of a work of art: aesthetic evaluation and artistic evaluation.
Roman Dykast
doaj   +1 more source

Performance Evaluation in the Arts

, 2023
Abstract Arts management research on performance evaluation has been characterized by an applied approach, focusing on providing arts organizations with performance evaluation models and techniques, rather than seeking to understand the meaning of performance and its evaluation in the specific contexts in which individual organizations ...
openaire   +1 more source

Protein Disulfide Isomerase Disassembles TDP‐43/G3BP1 Condensates and Antagonizes TDP‐43 Pathological Aggregates

Advanced Science, EarlyView.
Cytoplasmic aggregation of TDP‐43 is a common pathological feature in amyotrophic lateral sclerosis, frontotemporal lobar degeneration, and Alzheimer's disease with TDP‐43 pathology. This study reports that wild‐type PDI slows down phase separation of TDP‐43 through direct interaction with TDP‐43.
Jia‐Qi Liu, Hao Liu, Yu‐Xuan Sun, Yuying Li, Xiangyi Liu, Li‐Qiang Wang, Zhaofei Yang, Qi Fu, Xiaojiao Xu, Jie Chen, Yingshuang Zhang, Jun Zhou, Weidong Le, Mengchao Cui, Yi Liang   +14 more
wiley   +1 more source

Sleeping Beauty? A Prospective Study on the Prevalence of Sleep Problems and Their Potential Determinants in Professional Dancers

Sports Medicine - Open
Background Sleep is important for health and performance but has rarely been studied in professional dancers. The aim was to analyse the prevalence of sleep problems in professional dancers and their potential determinants at the beginning of and during ...
Astrid Junge, Rogier M. van Rijn, Janine H. Stubbe, Anja Hauschild   +3 more
doaj   +1 more source

Music Therapy and Other Music-Based Interventions in Pediatric Health Care: An Overview

Medicines, 2019
Background: In pediatric health care, non-pharmacological interventions such as music therapy have promising potential to complement traditional medical treatment options in order to facilitate recovery and well-being. Music therapy and other music-based
Thomas Stegemann, Monika Geretsegger, Eva Phan Quoc, Hannah Riedl, Monika Smetana   +4 more
doaj   +1 more source

Building audiences: Aboriginal and Torres Strait Islander arts [PDF]

, 2015
Building Audiences examines the barriers to and the strategies for increasing audiences in the Aboriginal and Torres Strait Islander arts sector. This research investigates the attitudes, beliefs and behaviours of current and potential audiences.
Brian J. Martin, Ruth Rentschler, Kerrie Bridson, Jody Evans, Tabitha White, Maree Clarke   +5 more
core  

Personalized Network‐Guided Neuromodulation Enhances Human Working Memory

Advanced Science, EarlyView.
A personalized neuromodulation framework combining individualized functional brain network targeting with real‐time neural decoding is introduced. Using concurrent TMS–fMRI, participant‐specific stimulation targets and optimal frequencies are identified. Only optimal‐frequency stimulation improves working memory across sessions.
Ahsan Khan, Hongming Li, Camille Blaine, Julie Grier, Ethan Hammett, Almaris Figueroa‐Gonzalez, Sarai Garcia, Romain Duprat, Justin Reber, Joseph Deluisi, Christos Davatzikos, Theodore D. Satterthwaite, Yong Fan, Desmond J. Oathes   +13 more
wiley   +1 more source

Self-reported Health Problems of Professional Dancers from Five German Opera Houses or State Theatres: A Prospective Study with Weekly Follow-ups during One Season

Sports Medicine - Open
Background Most studies on injuries of professional dancers used a medical-attention and/or time-loss definition and did not analyse all health problems. Further, almost all studies included just one company.
Astrid Junge, Rogier M van Rijn, Janine H Stubbe, Anja Hauschild   +3 more
doaj   +1 more source

Alberta performing arts policy [PDF]

, 1998
iii, 97 leaves : ill. ; 28 cm.Alberta's first arts legislation, the Cultural Development Act, was passed in 1946. It was followed by numerous policy initiatives to support the arts, including creation of facilities for training of artists, development of
Schindeler, Marda, University of Lethbridge. Faculty of Arts and Science   +1 more
core