Results 61 to 70 of about 5,122,542 (341)
Reducing Electricity Demand Charge for Data Centers with Partial Execution
, 2013 Data centers consume a large amount of energy and incur substantial electricity cost. In this paper, we study the familiar problem of reducing data center energy cost with two new perspectives. First, we find, through an empirical study of contracts from
Bash C. +6 more
core +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Vaccine: X, 2023 Objectives: Understanding COVID-19 vaccine hesitancy among migrant and refugee groups is critical for achieving vaccine equity. Therefore, we aimed to estimate the prevalence of COVID-19 vaccine acceptance among migrant and refugee populations.
Zainab Alimoradi +4 more
doaj +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Optimal algorithms for weighted 1-center problem in deterministic and stochastic tree networks
Alexandria Engineering Journal, 2020 This paper deals with two single facility location problems. The first problem is about the deterministic weighted (DW) 1-center of a deterministic tree network (DTN).
A.W. Aboutahoun, F. El-Safty
doaj +1 more source
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
A New Method for Research on the Center-Focus Problem of Differential Systems
Abstract and Applied Analysis, 2014 We will introduce Mironenko’s method to discuss the Poincaré center-focus problem, and compare the methods of Lyapunov and Mironenko. We apply the Mironenko method to discuss the qualitative behavior of solutions of some planar polynomial differential ...
Zhengxin Zhou
doaj +1 more source
Subset method for one-dimensional QCD
, 2013 We present a subset method which solves the sign problem for QCD at nonzero quark chemical potential in 0+1 dimensions. The subsets gather gauge configurations based on the center symmetry of the SU(3) group.
Bloch, Jacques +2 more
core +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
The Technological Problem Of Simulation Of The Logistics Center
, 2015 Planning of infrastructure and processes in logistic center within the frame of various kinds of logistic hubs and technological activities in them represent quite complex problem. The main goal is to design appropriate layout, which enables to realize expected operation on the desired levels. The simulation software represents progressive contemporary
Camaj, Juraj +3 more
openaire +1 more source