Results 81 to 90 of about 128,240,371 (320)
Advanced Science, EarlyView.Guided by spatial transcriptomics and clinical validation, a threaded microneedle platform enables precise layer‐specific delivery across the dermis and subcutaneous tissue. By addressing distinct pathogenic remodeling in different skin layers, this strategy coordinates compartment‐specific intervention, restores tissue architecture, and offers a ...
Fangzhou Xie +14 more
wiley +1 more source
June 1941 Uprising in Kretinga, Mažeikiai and Telšiai Counties
Genocidas ir Rezistencija, 2010 The topic of the article is the June 1941 Uprising in Kretinga, Mažeikiai and Telšiai counties. The work underlines that the Uprising emerged and the partisan squads were formed not spontaneously, since the underground participants in Kretinga ...
Alfredas Rukšėnas
doaj +1 more source
Advanced Science, EarlyView.SOX30 drives triple‐negative breast cancer (TNBC) metastasis through a dual mechanism: direct activation of the TNFR2/NF‐κB signaling cascade and subsequent CCL20‐mediated recruitment of tumor‐associated macrophages (TAMs) into the tumor microenvironment.
Pingping Gao +10 more
wiley +1 more source
Animal Models and Experimental Medicine, EarlyView.In this study, we established a novel mouse model of intracerebral hemorrhage (ICH) by stereotactically injecting thermosensitive PNIPAM hydrogel into the internal capsule to impose localized mechanical stress on the corticospinal tract, which provides a straightforward and reproducible tool for preclinical studies on focal mechanical stress–induced ...
Mingxi Li +11 more
wiley +1 more source
Journal of Virus Eradication, 2016 Background: The challenges of identifying acute HIV infection (AHI) have resulted in a lack of critical information on early AHI that constrains the development of therapeutics that are designed to eradicate HIV from the infected host.
Jintanat Ananworanich +20 more
doaj +1 more source
Association of DPP4 with esophageal stricture progression and the Hippo‐YAP pathway
Animal Models and Experimental Medicine, EarlyView.This study establishes a comprehensive translational platform for esophageal stricture (ES) research by integrating a novel rat model with clinically relevant porcine validation. This study identifies DPP4 as a gene of interest associated with ES following endoscopic submucosal dissection, demonstrating that prophylactic DPP4 inhibition attenuates ...
Rui Wu +5 more
wiley +1 more source
Theoretical and methodological foundations of research on the design of physical fitness and recreational technologies [PDF]
Физическое воспитание и студенческий спортHealth preservation and health promotion are among the most popular research topics in the modern world. Unfortunately, young people do not pay due attention to this issue, do not apply modern methods and ways to increase the body’s resistance to ...
Pestrikov, Evgenii A.
doaj +1 more source
Tectonics and Stratigraphy, 2019 Increasing requirements for environmental protection in the coal mining industry in Ukraine stipulates the need for new scientifically grounded methods for forecasting the content of toxic and potentially toxic elements in rock mass, mining waste and ...
V. Ishkov, Y. Kozii
semanticscholar +1 more source
Animal Models and Experimental Medicine, EarlyView.This study compared hypertrophic scar (HS) formation in SD rats at ear, back, and tail sites with or without mechanical tension. The ear model healed spontaneously by day 30. Dorsal full‐thickness excision (1 × 8 cm) produced moderate HS. In contrast, the tail tension model showed the greatest scar thickness, fibroblast density, collagen deposition ...
Lingyi Zhan +10 more
wiley +1 more source