Results 41 to 50 of about 4,219,336 (366)

Foreign policy conditionality of the Slovak Republic [PDF]

open access: yesAnnales Scientia Politica, 2023
On January 1, 1993, as a result of the breakup of the Czech and Slovak Federative Republics, a new state was created on the political map of Europe: the Slovak Republic.
Krzysztof Żarna
doaj  

Price effects of VAT introduction in Croatia [PDF]

open access: yes, 1997
This Occasional Paper is based on the research project “Analysis of the fiscal system of the Republic of Croatia at the introduction of value added tax” undertaken by the Institute of Public Finance and financed by the Ministry of Finance of the Republic
Dalic, Martina
core   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

Further description of bovine tuberculosis trends in the United Kingdom and the Republic of Ireland, 2003–2015

open access: yesThe Veterinary Record, 2018
Extending on earlier work, trends in bovine tuberculosis (bTB) from 2003 to 2015 are described for the countries of the UK and the Republic of Ireland using standardised definitions and measures.
S. More   +11 more
semanticscholar   +1 more source

The Republic of Science in the 1990s [PDF]

open access: yes, 1994
Research councils began as channels for state patronage of science (a widespread phenomenon after World War II) and were captured by the scientists: peer review of proposals, panels, board membership.
Rip, Arie
core   +4 more sources

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

Results from a Knowledge, Attitudes, and Practices Survey in Two Malaria Transmission Foci of Santo Domingo, Dominican Republic [PDF]

open access: hybrid, 2023
Hunter Keys   +5 more
openalex   +1 more source

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