Results 91 to 100 of about 886,761 (310)

On the Guarantee of the Realization of the Right to Education

open access: yesСибирское юридическое обозрение, 2017
The article reveals the issues of the essence and content of the guarantee of the realization of the right to education, the system of guarantees for the implementation of constitutional and legal principles and norms, including those that consolidate ...
Elena A. Kashtanova
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Technology is shaping the future of education: Striking the right balance between the old and new

open access: yes, 2018
As educators we need to be aware of and accepting of the fact that millennials have been raised in an environment that is significantly different to that of preceding generations – and consider how we can use the technology they are so fused with to ...
Ennis, C., McGraw-Hill Education
core  

Problems of exercising the right of education in the conditions of the informational and digital reality and AI development

open access: yesИзвестия высших учебных заведений. Поволжский регион: Общественные науки, 2022
Background. Currently, AI technologies and systems are being purposefully in-troduced into all spheres of society and the state, their influence is becoming more and more noticeable and tangible in the implementation of human rights, including basic ...
T.N. Balashova
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Education Policy and Education Practice Nexuses

open access: yes, 2023
This introductory chapter addresses the complex interrelations between education policy and education practice developed under new ways of governance.
Wermke, Wieland,   +2 more
core   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

The impact of COVID-19 on the right to education in India

open access: yes, 2021
The COVID-19 pandemic has highlighted the difficulty in striking a balance between two competing rights in a time of global crisis—the right to public health and the right to education—both fundamental rights enshrined under India’s ...
Star, Shaun
core  

Hospital School Program: The Right to Education for Long-Term Care Children. [PDF]

open access: yesInt J Environ Res Public Health, 2021
Caggiano G   +4 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy