Results 101 to 110 of about 886,761 (310)
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
People as Changemakers: Community based management for right to education
, 2010 This paper addresses the ways in which the community, a primary stakeholder in any education system, can influence the government's initiatives to carry out India's Right to Education Act of 2010.
Kapoor, Richa
core
Reconstituting the Right to Education [PDF]
, 2016 Confronting persistent and widening inequality in educational opportunity, advocates have regarded the right to education as a linchpin for reform. In the forty years since the Supreme Court relegated that right to the domain of state constitutional law,
Weishart, Joshua
core +1 more source
Education Policy Analysis Archives, 2010 This article seeks to address human rights issues from a triple perspective. First, conceptually locating human rights in the context of globalization and making a critique of the liberal conception of human rights.
Eduardo Salvador Vila Merino +1 more
doaj
A human rights approach: The right to education in the time of COVID-19: Commentary on COVID-19 Special Section. [PDF]
Child Dev, 2021 Fredman S.
europepmc +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
INTRODUCTION TO THE SPECIAL ISSUE ON THE RIGHT TO EDUCATION
Online Learning, 2019 n the 60 years since the Declaration, changes have swept higher education. The emergence of online education promises that growth in its quality, scale and breadth could insure that education becomes a right.
John R. Bourne +2 more
doaj +1 more source
COVID-19 and the right to education in Chile: An opportunity to revisit our social contract. [PDF]
Int Rev Educ, 2021 Gelber D +4 more
europepmc +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source