Results 51 to 60 of about 116,513 (258)
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Urban, Planning and Transport Research, 2014 Global city discourses rearticulate the relationships between the state, urban space and the global economy. At the local level, global city reconfigurations stamp the mark of a global economic order onto local citizenship practices.
Dallas Rogers, Michael Darcy
doaj +1 more source
‘Stay Home Without a Home’: Report from a webinar on the right to housing
Radical Housing Journal, 2020 This Update reports from a webinar on the impacts on the right to housing and linked political struggles of the lockdown measures put in place globally amid the Covid-19 pandemic.
Guya Accornero +6 more
doaj +1 more source
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Konut Hakkı ve Konut Sektörüne 2013-2016 Dönemi Konya Özelinde Bakış
Selçuk Üniversitesi Sosyal Bilimler Enstitüsü Dergisi, 2017 Barınma ihtiyacı, insanlığın var oluşundan bu yana karşılanması gereken bir olgudur. Birleşmiş Milletler İnsan Hakları Evrensel Bildirgesi ve bu bildirgenin somutlaşmasına olanak tanıyan farklı bir takım sözleşmelerde de konut hakkına, diğer bir ifadeyle,
Enes Yalçın, Selçuk Aslan
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Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Diversity or Displacement? Housing capital and the right to place
Oñati Socio-Legal Series, 2020 Increasing costs of housing and processes of gentrification are excluding poorer people from convenient areas of cities where they have traditionally lived. This paper responds to the loss of diversity being experienced in part of inner western of Sydney
Richard Mohr
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Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Town and Regional PlanningThe right to housing is a fundamental human right, but the paucity of context-specific legislation and policies on the right to housing makes housing inaccessible to a significant number of people residing in African cities.
John Mubangizi
doaj +1 more source