Results 71 to 80 of about 136,752 (325)

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Thatcherite ideology, housing tenure, and crime: the socio-spatial consequences of the right to buy for domestic property crime [PDF]

open access: yes, 2015
Our aim in this article is to explore the degree to which the changes produced in the provision of housing in England and Wales produced changes in the socio-spatial distribution of economic need and social deprivation, which in turn changed the ...
Colin Hay   +11 more
core   +1 more source

De la relégation à l’appropriation : (re)lire la citadinité à Khartoum au prisme de la transformation matérielle, sociale et symbolique de ses périphéries

open access: yesEchoGéo
In the context of the ongoing conflict in Sudan since April 2023, this article proposes to analyse the citadinities that have been constructed on the outskirts of Khartoum over the last two decades.
Corten Pérez-Houis, Alice Franck
doaj   +1 more source

Mua bán nhà ở có thời hạn - Mô hình Thụy Sĩ và những gợi mở cần dự liệu theo quy định của Luật Nhà ở năm 2023

open access: yesTạp chí Khoa học Pháp lý Việt Nam
The sale of residential housing with a fixed term is a relatively new legal framework introduced in the 2023 Housing Law, building upon the provisions on the right to agree on time-limited home ownership previously stipulated in the 2014 Housing Law ...
Dương Kim Thế Nguyên   +1 more
semanticscholar   +1 more source

Universal health care in 21st century Americas.

open access: yesThe Lancet, 2019
1570 www.thelancet.com Vol 393 April 20, 2019 Despite considerable progress, the Pan American Health Organization (PAHO) estimates that 30% of the population of the Americas still do not have access to the health care they need because of multi faceted ...
The Lancet
semanticscholar   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

The Voluntary Right to Buy pilot: Additional analysis of completions [PDF]

open access: yes, 2017
This report builds on detailed analysis of the lessons from the pilot programme for the Voluntary Right to Buy (VRTB). The introduction of the right to buy (RTB) for eligible tenants in specified housing association dwellings was a manifesto commitment ...
Reeve, Kesia, Pattison, Ben, Cole, Ian
core  

Redrawing the border through the 'Right to Rent': exclusion, discrimination and hostility in the English housing market [PDF]

open access: yes, 2019
The UK Immigration Act 2016 is central to the Conservative Government’s drive to create a more hostile environment for potential migrants and current ‘illegal’ migrants residing in the UK.
Tokarczyk, Trudi   +4 more
core   +1 more source

Making sense of place-making in Penang island’s affordable housing schemes: voices from key stakeholders

open access: yesInternational Journal of Urban Sustainable Development, 2020
The housing agenda shifted its paradigm from housing as basic needs to housing as rights. It became widely contested when ‘affordable housing’ entered the discourse.
Suet Leng Khoo, Kuan Heong Woo
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

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