Results 41 to 50 of about 41,270 (311)
A hybrid CFGTSA based approach for scheduling problem: a case study of an automobile industry [PDF]
In the global competitive world swift, reliable and cost effective production subject to uncertain situations, through an appropriate management of the available resources, has turned out to be the necessity for surviving in the market. This inspired the
Vikas Kumar +13 more
core +1 more source
The compact energy recovery linac (cERL) has been developed for industrial applications since 2017. Applications such as free electron laser require a compressed beam with a small energy spread and transverse emittance.
Miho Shimada +9 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Simulation Study of Microwave Heating with Nanoparticle Diffusion for Tumor Ablation [PDF]
Microwave heating is one of the prominent treatment procedure that elevates body temperature using microwave energy to damage tumor cells. However, healthy tissues can also absorb microwave energy causing undesired damage.
Kazi Mahdi Mahmud +1 more
doaj +1 more source
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Extending the automated zoning procedure to reconcile incompatible zoning systems
This paper concerns the problem of matching incompatible zonal geographies, for example in the context of comparing census outputs over time. The automated zoning procedure (AZP) proposed by Openshaw (1977) is reviewed and extended to permit its ...
Martin, D.
core +1 more source
We analyze the amplitude-frequency, phase-frequency, signal amplification, linear range, and vector characteristics of the built-in vector atomic magnetometer operating at extreme off-resonance condition in a nuclear magnetic resonance oscillator, which ...
Qiyuan Jiang +4 more
doaj +1 more source
An Extended Flood Characteristic Simulation Considering Natural Dependency Structures
The design of a river-basin-specific flood hydrograph generator based on gauge records enables the generation of synthetic flood hydrographs for the dimensioning of hydraulic structures.
Marco Albert Öttl +4 more
doaj +1 more source
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source

