Monte Carlo Procedure for Protein Design
, 1998 A new method for sequence optimization in protein models is presented. The approach, which has inherited its basic philosophy from recent work by Deutsch and Kurosky [Phys. Rev. Lett.
A. D. Sokal +17 more
core +2 more sources
Jastrow correlation factor for atoms, molecules, and solids [PDF]
, 2004 A form of Jastrow factor is introduced for use in quantum Monte Carlo simulations of finite and periodic systems. Test data are presented for atoms, molecules, and solids, including both all-electron and pseudopotential atoms.
A. Malatesta +9 more
core +2 more sources
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Distribution of Diffusion Constants and Stokes-Einstein Violation in supercooled liquids
, 2014 It is widely believed that the breakdown of the Stokes-Einstein (SE) relation between the translational diffusivity and the shear viscosity in supercooled liquids is due to the development of dynamic heterogeneity i.e.
Karmakar, Smarajit, Sengupta, Shiladitya
core +1 more source
Cool Roof Impact on Building Energy Need: The Role of Thermal Insulation with Varying Climate Conditions [PDF]
, 2019 Cool roof effectiveness in improving building thermal-energy performance is affected by different variables. In particular, roof insulation level and climate conditions are key parameters influencing cool roofs benefits and whole building energy ...
Cabeza, Luisa F. +5 more
core +2 more sources
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
UAV-Enabled Wireless Backhaul Networks Using Non-Orthogonal Multiple Access
IEEE Access, 2021 Owing to their potential mobility and agility, unmanned aerial vehicles (UAVs) have captured predominant interests in sustaining 5G wireless communication and beyond. In this paper, we scrutinize the downlink transmission of UAV-enabled wireless backhaul
Nadia Iradukunda +4 more
doaj +1 more source
Optimizing the control system of cement milling: process modeling and controller tuning based on loop shaping procedures and process simulations [PDF]
Brazilian Journal of Chemical Engineering, 2014 Based on a dynamical model of the grinding process in closed circuit mills, efficient efforts have been made to optimize PID controllers of cement milling. The process simulation is combined with an autoregressive model of the errors between the actual process values and the computed ones. Long term industrial data have been used to determine the model
openaire +3 more sources
Machine Learning-Based Elastic Cloud Resource Provisioning in the Solvency II Framework [PDF]
, 2016 The Solvency II Directive (Directive 2009/138/EC) is a European Directive issued in November 2009 and effective from January 2016, which has been enacted by the European Union to regulate the insurance and reinsurance sector through the discipline of ...
Casarano, Giuseppe +5 more
core +2 more sources
Survivin and Aurora Kinase A control cell fate decisions during mitosis
Molecular Oncology, EarlyView.Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source