Results 81 to 90 of about 684,854 (301)

Analysis of Treacher Collins syndrome 4‐associated mutations in Schizosaccharomyces pombe

open access: yesFEBS Open Bio, EarlyView.
Fission yeast models carrying Treacher Collins syndrome type 4‐associated mutations reveal that impaired processivity of RNA polymerase I leads to defective rRNA transcription. This study highlights the essential role of a conserved arginine residue in Pol I elongation and provides mechanistic insight into the pathogenesis of ribosomopathies.
Kei Kawakami, Hiroaki Kato
wiley   +1 more source

学習者、教授者、メディア : 外国語教育研究の統合的枠組みに向けて [PDF]

open access: yes, 2007
This article provides an integrated framework for foreign language (FL) education research. This framework has three principal components or spheres: learner, teacher, and media, all of which can contribute to the realization of “learner autonomy” via ...
Takeuchi Osamu, 竹内 理
core   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

open access: yesFEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig   +7 more
wiley   +1 more source

On Entanglement and Separability

open access: yes, 2016
We propose two necessary sufficient (NS) criteria to decide the separability of quantum states. They follow from two independent ideas: i) the Bloch-sphere-like-representation of states and ii) the proportionality of lines (rows, columns etc.) of certain
Mehendale, Dhananjay P.
core  

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

open access: yesFEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

КОНЦЕПТОСФЕРА ГІДНІСТЬ В УКРАЇНСЬКІЙ ЛІНГВОКУЛЬТУРІ (Conceptosphere Dignity in Ukrainian lingua-culture) [PDF]

open access: yes, 2014
У статті проаналізовано концептосферу ГІДНІСТЬ у свідомості носіїв української мови та культури за допомогою методу когнітивної дефініції. Використано лексикографічні джерела, результати анкетування і корпусні матеріали.
Чабан, В. (V. Сhaban)
core  

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

open access: yesFEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada   +5 more
wiley   +1 more source

EVALUATION FUNCTION OF THE ENGLISH-LANGUAGE BORROWINGS IN THE MODERN LANGUAGE PERIOD

open access: yesГуманитарные и юридические исследования, 2021
The article deals with phraseological units of the English language with ethnonym component. To determine national and cultural particularity of the English ethnic group we distinguish and analyse phraseological units with ethnonym component which have a
P. V. Pantukhova, I. S. Reshetova
doaj  

Glimpses of the Octonions and Quaternions History and Todays Applications in Quantum Physics

open access: yes, 2008
Before we dive into the accessibility stream of nowadays indicatory applications of octonions to computer and other sciences and to quantum physics let us focus for a while on the crucially relevant events for todays revival on interest to ...
A.K. Kwaśniewski   +19 more
core   +2 more sources

The Impact of Tilburg Frailty on Poststroke Fatigue in First‐Ever Stroke Patients: A Cross‐Sectional Study With Unified Measurement Tools and Improved Statistics

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Poststroke fatigue (PSF) and frailty share substantial overlap in their manifestations, yet previous research has yielded conflicting results due to the use of heterogeneous frailty assessment tools. Objective To evaluate the independent impact of frailty on PSF using a unified measurement system (Tilburg Frailty Indicator, TFI ...
Chuan‐Bang Chen   +6 more
wiley   +1 more source

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