Results 181 to 190 of about 1,516,630 (298)

RNF213 Is an Interferon‐Stimulated Gene That Targets Influenza A Virus NP and Activates MDA5 to Restrict Infection

Advanced Science, EarlyView.
RNF213 is characterized as a dual‐functional antiviral effector. It directly mediates the degradation of the influenza A virus nucleoprotein (NP) while simultaneously activating the MDA5‐mediated innate immune signaling pathway. This coordinated response establishes a powerful host defense system against viral infection. ABSTRACT Influenza A virus (IAV)
Haoning Li, Yuying Zhang, Jingjing Wang, Qianqian Zhang, Hailiang Sun, Fanhua Wei   +5 more
wiley   +1 more source

Prey-Foraging Patterns in a Complex Landscape of Fear. [PDF]

Ecol Evol
Sysiak M, Pietrzak B, Mikulski A.
europepmc   +1 more source

AutomataGPT: Transformer‐Based Forecasting and Ruleset Inference for Two‐Dimensional Cellular Automata

Advanced Science, EarlyView.
We introduce AutomataGPT, a generative pretrained transformer (GPT) trained on synthetic spatiotemporal data from 2D cellular automata to learn symbolic rules. Demonstrating strong performance on both forward and inverse tasks, AutomataGPT establishes a scalable, domain‐agnostic framework for interpretable modeling, paving the way for future ...
Jaime A. Berkovich, Noah S. David, Markus J. Buehler   +2 more
wiley   +1 more source

Unveiling the early defense response dynamics in grapevines against Plasmopara viticola by single-cell transcriptomics. [PDF]

Genome Biol
Yao X, Xu Z, Xi Y, He X, Gao Q, Lu J, Fu P.   +6 more
europepmc   +1 more source

ADMINISTRATIVE AND LEGAL PRINCIPLES OF THE FORMATION OF THE STATE DEFENSE ORDER IN UKRAINE

Scientific Journal of Public and Private Law, 2023
openaire   +1 more source

Decoding Triphenotypic Neutrophils in Cervical Cancer Evolution and Targeting SPP1+/GBP1+/ELOVL5+ Tumor‐Associated Neutrophils to Sensitize Immunotherapy

Advanced Science, EarlyView.
The functional schematic diagram of tumor associated neutrophils. Abstract Enhancing cervical cancer (CC) immunotherapy requires deciphering the heterogeneous tumor immune microenvironment (TIME), particularly neutrophil phenotypic dynamics. Here, 1) we collected 543 CC cases to find that patients with elevated neutrophil levels have a higher incidence
Xingyu Chang, Xinyu Qu, Tingting Ren, Tong Wu, Weiyong Gu, Jingxin Ding, Keqin Hua, Junjun Qiu   +7 more
wiley   +1 more source

TopoSleuth, a decoy-based multi-layered defense framework for securing SDN topology discovery. [PDF]

Sci Rep
Shoaib M, Amjad MF, Islam FU, Tahir S, Sattar K.   +4 more
europepmc   +1 more source

De Novo Multi‐Mechanism Antimicrobial Peptide Design via Multimodal Deep Learning

Advanced Science, EarlyView.
Current AI‐driven peptide discovery often overlooks complex structural data. This study presents M3‐CAD, a generative pipeline that leverages 3D voxel coloring and a massive database of over 12 000 peptides to capture nuanced physicochemical contexts.
Xiaojuan Li, Haifan Gong, Yue Wang, Yinuo Zhao, Lixiang Li, Peijing Bao, Qingzhou Kong, Jialu Fu, Boyao Wan, Yumeng Zhang, Jinghui Zhang, Jiekun Ni, Zhongxue Han, Xueping Nan, Kunping Ju, Longfei Sun, Yuerui Ma, Huijun Chang, Mengqi Zheng, Yanbo Yu, Xiaoyun Yang, Xiuli Zuo, Haina Wang, Yanqing Li   +23 more
wiley   +1 more source

Living the Charisms of the Sovereign Military Order of Malta in Modern Medicine:Catholic Healthcare Professionals Enact Malta's Principles in Routine Patient Care. [PDF]

Linacre Q
Kozak R.
europepmc   +1 more source

Brief for Amici Curiae AARP et al., United States Department of Housing and Urban Development v. Rucker et al., Nos. 00-1770 & 00-1781 (U.S. Dec. 20, 2001) [PDF]

, 2001
Edelman, Peter B.
core   +1 more source