Results 41 to 50 of about 54,180 (240)
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Tyragetia, 2019 In the autumn of 1185, the anti-Byzantine rebellion of the Vlachs in Haemus took place, led by the brothers Peter and Asen; it was caused by the abuses and excessive taxation of Emperor Isaac II Angelos.
Mărculeţ Vasile
doaj
Islam in China: Uyghurs in Crisis [PDF]
, 2020 Islam has been in China for hundreds of years and has been the religion to ten people groups in China, including the Uyghur people group. The Uyghurs have been under China’s domain since the mid-1700s and since then have stood out among the fifty-five ...
Baez, Isabella
core +1 more source
Mothering a nation : the gendered memory of Kenya’s Mau Mau rebellion [PDF]
, 2015 textThis paper approaches fiction as a site of gendered history and memory and presents two pieces of literature by Kenyan authors - Passbook Number F.47927 by Muthoni Likimani and The Trial of Dedan Kimathi by Ngũgĩ wa Thiong'o and Micere Githae Mugo ...
Murimi, Wanjira
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Pu-Ku Huai-En, The great Turk General of T'ang Dynasty
Ankara Üniversitesi Dil ve Tarih-Coğrafya Fakültesi Dergisi, 2017 Pu-Ku Huai-en, one of the most important commanders during rise of the T'ang Dynasty, is Turkish origin. After the collapse of the first Gokturk state, Pu-ku tribe entered into the sovereignty of China, as a lot of Turkish tribes accepting Chinese ...
Tilla Deniz BAYKUZU
doaj
The North Star and the Atlantic 1848 [PDF]
, 2014 This article explores the coverage of the 1848 uprisings in Europe by the North Star, a black newspaper edited by Frederick ...
Benjamin Fagan
core +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Rural masters and urban militants in early twentieth-century South Africa [PDF]
, 2017 White farmers in South Africa, a landowning class that subordinated black tenants and workers, also participated in the suppression of white workers’ movements before and after the First World War.
Bradford +9 more
core +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source