Results 51 to 60 of about 54,180 (240)

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Turning Blind Eyes and Profits: The Foreign Role in Argentina’s Dirty War [PDF]

open access: yes, 2008
When faced with social unrest and an inability to participate in the political sphere, conflict and rebellion blossom. When economics preside over politics, all interaction is divisive and will always be composed of varying layers of two groups: the ...
Krupski, Brittany
core   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

James Peters, Military Photography and the Northwest Campaign, 1885 [PDF]

open access: yes, 2012
In June 1884, the noted buffalo hunter Gabriel Dumont led a delegation of Métis from the Batoche settlement, in what is now Saskatchewan, to Montana in the United States to search out Louis Riel.
Cooke, Owen
core   +1 more source

From law and order to pacification: Britain's suppression of the Arab revolt in Palestine,1936-39 [PDF]

open access: yes, 2010
The official published version of this article can be found at the link below.This article examines British human rights abuses against noncombatants during the 1936–39 Arab Revolt in Palestine, contextualizing brutality in Palestine within British ...
Hughes, M
core   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

open access: yesFEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold   +11 more
wiley   +1 more source

Post-apocalyptic protest, or ideological deformation of the "archetypical family" in the movie "Snowpiercer" / Постапокалиптический протест, или идеологическая деформация «архетипического семейства» в фильме «Сквозь снег»

open access: yesИндустрии впечатлений: Технологии социокультурных исследований
The article analyzes the film Through the Snow (2013), directed by Pong Jun-ho, as a multi-layered socio-political dystopia that embodies archetypal scenarios of an isolated and simultaneously dynamic post-apocalyptic society. The film's central theme is
Sergey Malenko / Сергей Анатольевич Маленко   +1 more
doaj   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

Destroying the Right Arm of Rebellion: Lincoln’s Emancipation Proclamation

open access: yes, 2019
Lincoln\u27s Emancipation Proclamation was a gamble. If it were to succeed, it could cripple the economy of the South, decimating its war effort, drive the border states to accept compensated emancipation, ending slavery as an institution in the United ...
Pontz, Benjamin
core  

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