Results 41 to 50 of about 1,306,548 (297)

An adequate logic for full LOTOS [PDF]

open access: yes, 2000
We present a novel result for a logic for symbolic transition systems based on LOTOS processes.
Calder, Muffy   +2 more
core   +6 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Symbolic Violence against Women as a Social and Cultural System

open access: yesFuori Luogo, 2023
The focus of this article is the system culture and society have availed themselves of down through the ages to enact symbolic violence against women.
Monica Gammaitoni
doaj   +1 more source

Symbolic integration [PDF]

open access: yesCommunications of the ACM, 1971
Three approaches to symbolic integration in the 1960's are described. The first, from artificial intelligence, led to Slagle's SAINT and to a large degree to Moses' SIN. The second, from algebraic manipulation, led to Manove's implementation and to Horowitz' and Tobey's reexamination of the Hermite algorithm for integrating rational functions.
openaire   +2 more sources

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Lower Bounds for Symbolic Computation on Graphs: Strongly Connected Components, Liveness, Safety, and Diameter

open access: yes, 2017
A model of computation that is widely used in the formal analysis of reactive systems is symbolic algorithms. In this model the access to the input graph is restricted to consist of symbolic operations, which are expensive in comparison to the standard ...
Chatterjee, Krishnendu   +3 more
core   +1 more source

Compositional abstraction and safety synthesis using overlapping symbolic models [PDF]

open access: yes, 2017
In this paper, we develop a compositional approach to abstraction and safety synthesis for a general class of discrete time nonlinear systems. Our approach makes it possible to define a symbolic abstraction by composing a set of symbolic subsystems that ...
Girard, Antoine   +2 more
core   +2 more sources

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Approximately bisimilar symbolic models for nonlinear control systems [PDF]

open access: yes, 2007
Control systems are usually modeled by differential equations describing how physical phenomena can be influenced by certain control parameters or inputs.
Girard, Antoine   +2 more
core   +5 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Home - About - Disclaimer - Privacy