Results 61 to 70 of about 1,306,548 (297)

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

open access: yesFEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti   +3 more
wiley   +1 more source

Symbolic Synchronization and the Detection of Global Properties of Coupled Dynamics from Local Information

open access: yes, 2006
We study coupled dynamics on networks using symbolic dynamics. The symbolic dynamics is defined by dividing the state space into a small number of regions (typically 2), and considering the relative frequencies of the transitions between those regions ...
Atay   +3 more
core   +1 more source

Evaluative conditioning as a symbolic phenomenon: on the relation between evaluative conditioning, evaluative conditioning via instructions, and persuasion [PDF]

open access: yes, 2016
Evaluative conditioning (EC) is sometimes portrayed as a primitive way of changing attitudes that is fundamentally different from persuasion via arguments.
De Houwer, Jan, Hughes, Sean Joseph
core   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

open access: yesFEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao   +3 more
wiley   +1 more source

Composing the Symbolic

open access: yesAisthesis, 2015
An excerpt from Sergei M. Eisenstein's memoirs describing a night visit to the museum of Chichén Itzá in Mexico is set forth as a real life example reflecting, both from a visual and theoretical perspective, the architecture of Aby Warburg's Bilderatlas ...
Daniela Sacco
doaj   +3 more sources

Warburg Effects in Cancer and Normal Proliferating Cells: Two Tales of the Same Name

open access: yesGenomics, Proteomics & Bioinformatics, 2019
It has been observed that both cancer tissue cells and normal proliferating cells (NPCs) have the Warburg effect. Our goal here is to demonstrate that they do this for different reasons.
Huiyan Sun   +4 more
doaj   +1 more source

SDRL: Interpretable and Data-efficient Deep Reinforcement Learning Leveraging Symbolic Planning

open access: yes, 2019
Deep reinforcement learning (DRL) has gained great success by learning directly from high-dimensional sensory inputs, yet is notorious for the lack of interpretability.
Gustafson, Steven   +3 more
core   +1 more source

ToyArchitecture: Unsupervised Learning of Interpretable Models of the World

open access: yes, 2020
Research in Artificial Intelligence (AI) has focused mostly on two extremes: either on small improvements in narrow AI domains, or on universal theoretical frameworks which are usually uncomputable, incompatible with theories of biological intelligence ...
Andersson, Simon   +12 more
core   +1 more source

The Symbolic Dynamics Of Multidimensional Tiling Systems [PDF]

open access: yes, 2003
We prove a multidimensional version of the theorem that every shift of finite type has a power that can be realized as the same power of a tiling system.
Coven, E. M.   +3 more
core   +2 more sources

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