Results 41 to 50 of about 410,814 (262)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
University proceedings. Volga region. Technical sciences
Известия высших учебных заведений. Поволжский регион:Технические наукиBackground. The purpose of the research is to develop a computer model for optimizing the loading of machines of the same classification group, but of different types, of the existing fleet of technological equipment of the enterprise.
V.V. Konovalov +3 more
doaj +1 more source
Journal of NeuroinflammationBackground and purpose Vascular cognitive impairment (VCI) is strongly linked to blood-brain barrier (BBB) dysfunction. This study investigated whether Tubuloside B (Tub-B), a primary bioactive compound of Cistanche tubulosa, ameliorates cognitive ...
Mingli He +8 more
doaj +1 more source
Acoustics aspects of technological process in the rock disintegration [PDF]
Acta Montanistica Slovaca, 2007 The paper describes some results of monitoring and aspects of the acoustic signal in the rock disintegration on the drillig stand of the Institute of Geotechnics, SAS in Košice.
Jozef Futó, František Krepelka
doaj
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
The Technological Process of Forging Blank Camshaft
Scientific Journal of Gdynia Maritime University, 2017 The article presents technological process of forging blank camshafts. It describes materials used on the camshafts blanks. The paper also sets out the conditions for the selection of manufacturing technology of semi-finished products.
K. Panasiuk
doaj
Digital control over the working process – technological and legal aspects [PDF]
Икономика и компютърни науки, 2020 The purpose of this article is to examine two main aspects of the control over the working process – technological and legal. In their interconnection they reflect the new means, through which the employers perform their functions on management and ...
Andriyana Andreeva, Oleg Asenov
doaj
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Prospects for modernization of technological machine tools in the format of the Industry 4.0 concept
Известия высших учебных заведений. Поволжский регион:Технические наукиBackground. Digital transformation creates opportunities for the transition of industry to a new level of production, but requires the modernization of technological equipment to a digital technological system.
Yu.L. Chigirinskiy +3 more
doaj +1 more source