Results 51 to 60 of about 412,695 (262)
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
DESIGN OF THE PEDAGOGICAL PROCESS ON A TECHNOLOGICAL BASIS
Вестник Мининского университета, 2017 The article deals with the design of the pedagogical process as design objectives, contents, forms of organization and teaching methods; describes the design activity of the teacher on the methodological, general pedagogical, technological levels of ...
S. M. Markova, S. A. Tsyplakova
doaj +2 more sources
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
MPROVING THE TECHNOLOGICAL WELDING PROCESS IN THE CONDITIONS OF SUSTAINABLE DEVELOPMENT [PDF]
Annals: Series on engineering sciences (Academy of Romanian Scientists), 2020 In the current conditions of sustainable development requirements, it is important to evaluate the activities of companies in the industry. This assessment is important from the perspective of improving the impact of organizations on the environment ...
Larisa IVAȘCU, Lucian-Ionel CIOCA
doaj
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Thermodynamic modeling of the borbarium ferroalloy smelting technological process
Metalurgija, 2020 A complete thermodynamic modeling of chemical transformations during carbothermic reduction of barium and boron from oxides has been performed. It was shown that during the processing of charge with a high BaO: BaO:B2O3(3:1), barium carbide (BaC2), iron ...
A. Akberdin +3 more
doaj
Modeling of the technological process of convective drying of lumber
Весці Нацыянальнай акадэміі навук Беларусі: Серыя фізіка-тэхнічных навук, 2019 A calculation of the technological process of lumber drying in convection drying chamber of periodic action is presented. For this purpose, a three-dimensional geometric model of a drying chamber with a lumber pile is developed.
V. A. Sychevskii
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source