Results 141 to 150 of about 1,547,004 (264)

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

FEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai, Yong Xu, Jingjing Ma, Ratchanee Duangrat, Chen Yan, Jingyan Liang, Hua Wei, Bin Jiang, Tao‐Sheng Li   +8 more
wiley   +1 more source

Wave propagation in a generalized magneto-micropolar thermoelastic medium with gravity and initial stress. [PDF]

Sci Rep
Salah DM, Abd-Alla AM, Aljohani MA.
europepmc   +1 more source

Relaxation of the Temperature of a Plate Placed in a Medium with a Lower Temperature

Tyumen State University Herald. Physical and Mathematical Modeling. Oil, Gas, Energy, 2017
openaire   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Three-Dimensional Pore-Scale Numerical Study of the Impact of Operation Parameters on Ammonia-Methane Premixed Combustion in a Double-Layer Spherical Stacked Porous Medium Burner. [PDF]

ACS Omega
Li D, Tan F, Wang X, Xu J, Wang S, Li F, Zhu T, Zhu L, Wu Z, Liao M.   +9 more
europepmc   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Peristaltic transport and thermodynamic analysis of hybrid nanofluids in porous media using physics-informed neural networks. [PDF]

Discov Nano
Vaseem M, Uddin Z, Upreti H.
europepmc   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Light-activated thiomaleimide crosslinking stabilizes collagen mimetic peptide triple helix.

Chem Commun (Camb)
Castro RA, Gammanchiralage S, Price C, Kloxin AM.   +3 more
europepmc   +1 more source

Preparation and Performance Study of Three-Layer Composite Filter Media for Channel-Type Ultra-Low Penetration Air Filters. [PDF]

Nanomaterials (Basel)
Li M, Wang D, Wang Y, Xie J, Liu Y, Liang Y, Kang J, Wang H.   +7 more
europepmc   +1 more source