Results 51 to 60 of about 410,901 (306)

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

The Changing World of Work: What Should We Ask of Higher Education? [PDF]

open access: yes, 2015
There is a pervasive anxiety in America about the future of higher education. Spiraling costs combined with seismic changes in the American workplace raise questions about whether a bachelor's degree is still worth the cost.
Scott London
core  

The Northern Ireland peace process in an age of austerity [PDF]

open access: yes, 2012
The steady drip of dissident Republican attacks forms the backdrop to this special issue of Political Quarterly. Moreover, this comes at a time of economic austerity, when Northern Ireland faces unprecedented cuts to its public sector-dominated economy ...
Kaufmann, Eric P.
core   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Love and Friendship in the Lysis and the Symposium: Human and Divine [PDF]

open access: yes, 2008
The paper claims that we cannot understand properly Platonic conception of love and friendship unless we read the Lysis in the light of the Symposium and vice verse.
Jinek, Jakub
core  

The Jury System in Contemporary Ireland: In the Shadow of a Troubled Past [PDF]

open access: yes, 1999
Jackson et al discuss the distinctive features of criminal trial by jury in Ireland, both north and south, to explain how the jury continues to survive within modern Ireland and how it also has managed to decline in ...
Jackson, John D.   +2 more
core   +2 more sources

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

open access: yesMolecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad   +12 more
wiley   +1 more source

Révolution française de 1789 contre Temps des troubles russe

open access: yesRevue des études slaves, 2019
Interpreting the Russian Revolution of 1917: French Revolution of 1789 versus Russian-Time of Troubles The French Revolution of 1789 is a common topic in the language and in the symbols of the Russian Revolution of 1917.
Catherine Depretto
doaj   +1 more source

Goal → New Heuristic Model of Ideality: Logos → Coincidentia Oppositorum → Primordial Generating Structure [PDF]

open access: yes, 2017
Fundamental knowledge endures deep conceptual crisis manifested in total crisis of understanding, crisis of interpretation and representation, loss of certainty, troubles with physics, crisis of methodology. Crisis of understanding in fundamental science
Rogozhin, Vladimir
core  

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