Results 61 to 70 of about 2,396,170 (309)
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Indoctrination Against Women in "The Lowland" by Jhumpa Lahiri
Indoctrination is one form to limit women's space unnoticed. Through indoctrination, a woman will not feel that her space of motion has been restricted.
Tomi Arianto, Ambalegin Ambalegin
doaj +1 more source
Tradition as a Communication System. A Pragmatic Approach [PDF]
A context of my paper is the debate on reason, tradition and traditional communities, in which this moral and epistemological issues were discussed as a part of general socio-philosophical theory of modernity.
Grad, Paweł
core
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
American poetry: the divided tradition
What is American poetry? This paper is a history of the various answers poets have given to that question. They include Whitman's creation of a new form for poetry, one to replace those inherited from England.
Dolan, Paul
doaj +1 more source
The Criticism of Masnavi Researches based on Mowlavi’s Mysticism Tradition and Disposition [PDF]
The importance of Masnavi on the one hand, and the increasing tendency for writing academic articles on the other hand has led to the creation of numerous and varied articles on this work. Each of these articles, from a particular point of view, seeks to
Aliasghar Mirbagherifard +2 more
doaj +1 more source
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Eternity and Vision in Boethius [PDF]
Boethius and Augustine of Hippo are two of the fountainheads from which the long tradition of regarding God’s existence as timelessly eternal has flowed, a tradition which has influenced not only Christianity, but Judaism and Islam, too.
Helm, Paul
core +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source

