Results 41 to 50 of about 179,934,146 (216)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Individual Differences and Metacognitive Knowledge of Visual Search Strategy [PDF]

, 2011
A crucial ability for an organism is to orient toward important objects and to ignore temporarily irrelevant objects. Attention provides the perceptual selectivity necessary to filter an overwhelming input of sensory information to allow for efficient ...
Proulx Michael J., Proulx, MJ, Michael J Proulx, Michael J. Proulx   +3 more
core   +2 more sources

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Devices for remote continuous monitoring of people with Parkinson’s disease: a systematic review and cost-effectiveness analysis

Health Technology Assessment
Background Parkinson’s disease is a brain condition causing a progressive loss of co ordination and movement problems. Around 145,500 people have Parkinson’s disease in the United Kingdom.
Edward Cox, Ros Wade, Robert Hodgson, Helen Fulbright, Thai Han Phung, Nicholas Meader, Simon Walker, Claire Rothery, Mark Simmonds   +8 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

CURRENT LEVELS OF MEDICAL EXPOSURE IN RUSSIA

Радиационная гигиена, 2015
We considered conditions of patients’ medical radiation exposure in Russian diagnostic radiology and nuclear medicine basing on the data of our own research, of the Unified system of individual dose control and of some relevant literature.
M. I. Balonov, V. Ju. Golikov, I. A. Zvonova, S. A. Kal’nickij, V. S. Repin, S. S. Sarycheva, L. A. Chipiga   +6 more
doaj  

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Liquor permit information and resource directory

, 2002
Title from title screen (viewed July 28, 2004).; "Publication date: April 2002."; Electronic text (pdf; 28 p.).; Harvested from the web on 7/28/04As a liquor permit holder, it is your responsibility to know the state liquor laws and the rules of the Ohio
Ohio. Division of Liquor Control
core  

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Adaptive control of left ventricular bypass assist devices

, 2011
19831201~19831201紙本YNew York ...
McInnis, Bayliss C.; Guo, Zhong Wei; Lu, Po Chien; Wang, Jiun Chung, McInnis, B. C.; Guo, Z. W.; Lu, Po-chien   +1 more
core   +1 more source