Results 71 to 80 of about 179,934,146 (216)

Deepwater Horizon Response: Gulf of Mexico Oil Spill Response

open access: yes, 2010
This website served as the focal point for the Deepwater Horizon Unified Command, a group of organizations that had involvement with the British Petroleum (BP) explosion and oil spill that occurred in the Gulf of Mexico in April 2010.
Deepwater Horizon Unified Command
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Numerical Analysis, Circuit Simulation, and Control Synchronization of Fractional-Order Unified Chaotic System

open access: yes, 2019
The traditional method of solving fractional chaotic system has the problem of low precision and is computationally cumbersome. In this paper, different fractional-order calculus solutions, the Adams prediction–correction method, the Adomian ...
Guohui Li, Xiangyu Zhang, Hong Yang
core   +1 more source

Environmental and organisational drivers influencing the adoption of unified communications technology in South Africa [PDF]

open access: yes, 2011
Includes abstract.Includes bibliographical references (leaves 167-174).Even though Information technology (IT) adoption has been widely studied most of this research has been conducted from within a limited set of perspectives.
Pinnock, Michael Brian
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Research and Realization of the Simulation Test System for Train Control On-board Equipment

open access: yes, 2017
Aiming at the requirement of simulation test to train control on-board equipment, the overall technical scheme and the realization method of the simulation test system for train control on-board equipment were presented by analyzing the running ...
Research and Realization of the Simulation Test System for Train Control On-board Equipment
core   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Unified Accreditation Documentation [PDF]

open access: yes, 2015
The University of Maine System\u27s unified accreditation ...
University of Maine System   +1 more
core  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

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