Results 51 to 60 of about 104,612 (287)

Longitudinal Assessment of Biomarkers in ALS: Discriminative Biomarkers for Disease Progression and Survival

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To assess the association and discriminative performance of serum biomarkers with clinical disease progression and survival in patients with amyotrophic lateral sclerosis (ALS). Methods This retrospective study, conducted at Houston Methodist Hospital, Houston, TX, used longitudinal serum samples collected between January 2018 and ...
David R. Beers   +7 more
wiley   +1 more source

Real‐World Longitudinal Data on the Impact of Hydroxychloroquine Blood Level Monitoring on Lupus Outcomes: Results of a Prospective Longitudinal Cohort Study

open access: yesArthritis Care &Research, EarlyView.
Objective Hydroxychloroquine (HCQ) is a cornerstone therapy in systemic lupus erythematosus (SLE), but the weight‐based dosing does not account for clinical factors that can introduce individual variability in drug metabolism and clearance. We leveraged longitudinal data from a prospective SLE cohort to identify clinical factors that predict ...
Jay J. Patel   +6 more
wiley   +1 more source

Bias Plus Variance Decomposition for Survival Analysis Problems

open access: yesCoRR, 2011
Bias - variance decomposition of the expected error defined for regression and classification problems is an important tool to study and compare different algorithms, to find the best areas for their application. Here the decomposition is introduced for the survival analysis problem.
openaire   +2 more sources

Adaptive Observer for Coupled Wave PDE and Infinite ODE With Sampled Data and Unknown Input: Application to Brain Hemodynamics Estimation

open access: yesInternational Journal of Adaptive Control and Signal Processing, EarlyView.
This article proposes a convergent adaptive observer for a damped wave PDE and an infinite‐dimensional ODE coupled in cascade using sampled‐in‐space ODE state measurements. The proposed observer estimates the distributed states of the PDE and ODE along with unknown PDE parameters and spatial input.
Zehor Belkhatir   +2 more
wiley   +1 more source

Evaluation of genome similarities using a wavelet-domain approach

open access: yesRevista da Sociedade Brasileira de Medicina Tropical
INTRODUCTION: Tuberculosis is listed among the top 10 causes of deaths worldwide. The resistant strains causing this disease have been considered to be responsible for public health emergencies and health security threats.
Leila Maria Ferreira   +2 more
doaj   +1 more source

Zein‐Based Adhesives: Sustainable Extraction and Application in Bioadhesive Technologies

open access: yesAdvanced Engineering Materials, EarlyView.
Zein is extracted from corn gluten meal using a simple and scalable process with high yield (~90%). The resulting protein is applied in bioadhesives modified with Ca2+ and Fe3+ ions, exhibiting substrate‐dependent adhesion. The findings demonstrate competitive bonding performance and highlight the role of ionic interactions in tuning adhesion ...
Paula Bertolino Sanvezzo   +3 more
wiley   +1 more source

The cluster decomposition of the configurational energy of multicomponent alloys

open access: yesnpj Computational Materials
The cluster expansion method (CEM) is a widely used lattice-based technique in the study of multicomponent alloys. Despite its prevalent use, a clear understanding of expansion terms is lacking.
Luis Barroso-Luque, Gerbrand Ceder
doaj   +1 more source

Multiscale variation analysis of sea surface temperature in the fishing grounds of pelagic fisheries

open access: yesFrontiers in Marine Science
Sea surface temperature (SST) are the focus of attention in global climate discussion. In particular, for pelagic fisheries that depend on the marine environment, understanding and mastering changes in SST is of great significance for managing fisheries ...
Qixiang Lai, Qixiang Lai, Weifeng Zhou
doaj   +1 more source

Decomposition analysis of CO2 emission in ASEAN: an extended IPAT model

open access: yesEnergy Procedia, 2018
Association of Southeast Asian Nations (ASEAN) is one of the most diverse regions. 3.6% of global greenhouse-gas emissions was released in 2013 and is expected to rise substantially due to increasing population and income.
Jaruwan Chontanawat
semanticscholar   +1 more source

Variable Stiffness Flexure Structures Enabled by Phase‐Change Gallium and Adhesive Interfacial Locking for Soft Robotic Applications

open access: yesAdvanced Engineering Materials, EarlyView.
A flexure‐based variable stiffness structure is developed by integrating phase‐change modulation and adhesive interfacial locking of gallium. The design enables a wide stiffness variability, transitioning from soft, flexible behavior to rigid, load‐supporting performance.
Sungjin Kim   +2 more
wiley   +1 more source

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