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Antigenic diversity of Theileria annulata macroschizonts
Veterinary Parasitology, 1986A series of monoclonal antibodies has been produced which reacts with the intracellular macroschizont of Theileria annulata, and this series has been used to examine the level of antigenic diversity between and within stocks of the parasite in addition to species specificity within the genus.
B, Shiels +3 more
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Chemoprophylaxis of Theileria annulata and Theileria parva infections of calves with buparvaquone
Veterinary Parasitology, 1998A clinical trial testing the prophylactic effect of a 5 mg kg-1 dose of buparvaquone on either Theileria annulata or Theileria parva experimental infections of calves demonstrated its efficacy for periods of at least seven days. The drug given 1 h or seven days before 50% lethal T.
G M, Wilkie +6 more
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Control of Theileria annulata in Iran
Parasitology Today, 1988Tropical theileriosis or Mediterranean Coast Fever - caused by Theileria annulata - is a disease of cattle widely distributed across southern Europe, north Africa and central Asia. Its distribution broadly corresponds with that of its main ixodid tick vectors Hyalomma excavatum and H. detritum (Fig. 1).
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Antigens and immunity in Theileria annulata
Parasitology Today, 1988About 200 million cattle are believed to be at risk from the debilitating and often fatal effects of tropical theileriosis, caused by Theileria annulata. Currently, there is no very cheap effective drug for treatment of T. annulata infections, although the hydroxynophthoquinones parvaquone and buparvaquone are reported to give good results(1-4 ...
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The sting of Theileria annulata
Trends in Parasitology, 2001Tropical theileriosis is caused by the protozoan parasite Theileria annulata and affects cattle from the Mediterranean to China. The parasite, which is transmitted by ticks, infects leukocytes to form macro- and microschizonts – microschizonts produce merozoites that can infect red blood cells.
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The pathogenesis of anaemia in Theileria annulata infection
Research in Veterinary Science, 1976Calves infected by a field strain of Theileria annulata developed severe anaemia, which was accompanied by bilirubinaemia and the appearance of free serum autohaemagglutinin antibodies. Animals infected with an agamogenous strain (lacking erythrocytic forms) also became anaemic.
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Chemotherapy Against Theileria annulata
1981Though a large number of compounds have been tested against Theileria annulata during the last several decades, satisfactory therapy of the disease has not become available. Recently, three drugs — Imidocarb (El-Refaii & Michael, 1976; Sharma et al, 1977), Menoctone (McHardy, 1978; McHardy et al, 1976) and the closely-related Naphthoquinone, 993C (2 ...
B. S. Gill +4 more
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Virulence and Attenuation in Theileria Annulata
2002Virulence, whilst superficially a simple concept, upon deeper analysis shows considerable complexity. Here, we consider the multifaceted aspects of virulence revealed in the syndrome of tropical theileriosis. The causative pathogen, Theileria annulata, is shielded from direct immune attack since it resides within host macrophages.
R. Adamson, R. Hall
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Treatment of Theileria annulata infection in calves with parvaquone
Research in Veterinary Science, 1985Fifteen calves were infected by the injection of stabilate of a suspension of Hyalomma anatolicum anatolicum ticks infected with the Ankara strain of Theileria annulata. Three were kept untreated, as controls, and they all died of theileriosis. Three groups of four calves were treated intramuscularly with parvaquone (Clexon; Wellcome) when early signs ...
N, McHardy, D W, Morgan
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In vivo evidence for the resistance of Theileria annulata to buparvaquone
Veterinary Parasitology, 2010The present study describes an outbreak of tropical theileriosis cases refractory to buparvaquone treatment, which occurred in a small-size dairy farm in Tunisia. Out of seven treated cows, four died in spite of repeated buparvaquone injections (2.5 and 5 mg kg(-1)) and the monitoring of the affected cows showed no improvement of the course of the ...
Moez, Mhadhbi +5 more
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