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Systematic review and meta-regression analysis of the prevalence of tick-borne pathogens in ticks and livestock in Uganda from 1980 to 2024. [PDF]

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Chemotherapy of Theileria parva infection

Nature, 1976
EAST coast fever (ECF), the most important tick-borne disease of cattle in eastern and central Africa, is caused by the protozoan parasite Theileria parva. No successful therapy is available and mortality can reach 96% (ref. 1), although large doses of tetracyclines have some prophylactic effect2.
N, McHardy, A J, Haigh, T T, Dolan
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Cryopreservation of infective particles of Theileria parva

International Journal for Parasitology, 1973
Abstract Cryopreservation of infective particles of Theileria parva. International Journal for Parasitology 3: 583–587. Infective particles of Theileria parva , the causative organism of East Coast fever of cattle, were obtained from infected Rhipicephalus appendiculatus ticks, either by using an in vitro feeding technique or by grinding the ...
M P, Cunningham   +3 more
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Merogony in in vitro cultures of Theileria parva

Veterinary Parasitology, 2003
In vitro studies were focussed on the duration and cessation of merogony in Theileria parva infected blood lymphocyte cell cultures. The cultures were infected using purified tick stabilates as an alternative to in vitro infections, using sporozoites obtained by labour intensive dissections of salivary glands from infected ticks. After establishment of
Madder, M.   +7 more
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Chemoprophylaxis of Theileria annulata and Theileria parva infections of calves with buparvaquone

Veterinary Parasitology, 1998
A clinical trial testing the prophylactic effect of a 5 mg kg-1 dose of buparvaquone on either Theileria annulata or Theileria parva experimental infections of calves demonstrated its efficacy for periods of at least seven days. The drug given 1 h or seven days before 50% lethal T.
G M, Wilkie   +6 more
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Studies on Macroschizonts of Theileria parva

Research in Veterinary Science, 1961
SUMMARY A series of measurements was made of the schizonts of Theileria parva in the hope that these criteria might be used in the differential diagnosis of the theilerial species. Macroschizonts were found to have an average size of 4.8 μ, which was smaller than expected. They contained from 1 to 85 nuclei, with an average of 8.
S.F. Barnett   +2 more
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Infection of bovine monocyte/macrophage populations with Theileria annulata and Theileria parva

Veterinary Immunology and Immunopathology, 1989
Infection and transformation of cells of the bovine immune system by Theileria annulata and T. parva were compared. Preliminary experiments with mammary gland macrophages indicated that they were permissive to infection by T. annulata but only to a limited extent by T. parva.
E J, Glass   +3 more
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Theileria parva: Significance of leukocytes for infecting cattle

Experimental Parasitology, 1978
Abstract Using an artificial feeding technique, infective particles of Theileria parva were harvested in bovine blood in capillary tubes from prefed female Rhipicephalus appendiculatus over a 2-hr period. Inoculations of this blood feed pool invariably resulted in the establishment of patent East Coast fever in autogeneic or syngeneic cattle, i.e.
C G, Brown   +6 more
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The antitheilerial effects of Theileria parva parva reaction and recovery sera In vitro

International Journal for Parasitology, 1985
Abstract Peripheral blood leucocytes (PBL) of cattle were infected in vitro with the sporozoites of Theileria parva spp. The transformed cell lines were adapted to grow in sera from the PBL donors. The cattle were then infected with T. p. parva stabilate and either treated with parvaquone or the disease allowed to run its course. Sera harvested
T T, Dolan, D A, Stagg, L M, Njuguna
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Theileria parya: Kinetics of replication

Experimental Parasitology, 1969
Abstract The kinetics of replication of Theileria parva (Muguga) in the bovine host were studied using infections produced by 10 1 , 10 2 , and 10 3 ticks. It was found that the growth of the organism was exponential from at least days 11–21 and probably from the start of growth in the bovine host.
W F, Jarrett, G W, Crighton, H M, Pirie
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