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Immunization of Cattle Against Theileria Parva

1977
Throughout its distribution in East and Central Africa, East Coast fever (ECF) is considered to be the most important of the tick-borne diseases which inhibit the development of the livestock industry. At present, the only method of controlling the disease is by close-interval application of acaricides to cattle, in dips or sprays, to kill the tick ...
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Preliminary Experiments with Antigens of Theileria Parva (Theiler, 1904)

British Veterinary Journal, 1967
SUMMARY The agar gel precipitin test was used to study the antigens of Theileria parva. Fractions were prepared from pre- and post-infection blood and lymph glands from the same ox. Antisera were prepared on cattle by inoculating post-infection fractions prepared from blood and spleen in Freund’s adjuvant. At least four specific precipitin bands were
R N, Gourlay, D W, Brocklesby
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Growth of Theileria annulata and T. parva in tissue culture

Transactions of the Royal Society of Tropical Medicine and Hygiene, 1958
1. 1) Theileria annulata was grown in tissue culture for over 59 days from implants of infected spleen, lymph node or liver. Multiplication of the parasites occurred and the cultures were infective for cattle when tested after 17 and 42 days. This confirms earlier work by TsUR (Tchernomoretz), 1945. 2. 2) T.
D W, BROCKLESBY, F, HAWKING
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Artificial infection of the tick Rhipicephalus appendiculatus with Theileria parva

Research in Veterinary Science, 1979
Methods for infecting Rhipicephalus appendiculatus ticks with Theileria parva by injection and by artificial feeding were confirmed and compared. The injection method proved simpler and at best as effective and suggested improvements are described.
A R, Walker   +3 more
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The molecular basis of transformation of lymphocytes by Theileria parva infection

Seminars in Cell Biology, 1993
The protozoan intracellular parasites, Theileria parva and Theileria annulata, infect cattle and cause severe and fatal leukocytic proliferative diseases. The proliferation is dependent on the presence of the parasites in the host cell cytoplasm. T. parva-infected cells proliferate permanently in cell culture and exhibit many features characteristic of
R O, Williams, D A, Dobbelaere
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Aureomycin in Thieileria parva Infection

Nature, 1953
RECOGNITION of the selective action of quinine, atebrin and chloroquine on the haemotropic trophozoites of certain Plasmodium species, and that of plasmoquine on the exoerythrocytic trophozoites as well as on the gametocytes, forms the bases of modern chemotherapy of malaria in laboratory animals and in man.
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The effect of immunisation with BCG on Theileria parva infection in cattle

Research in Veterinary Science, 1980
Cattle were immunised with 10(8) bacillus Calmette-Guerin (BCG) organisms 32 days before challenge with a lethal dose of Theileria parva stabilate. The disease reactions of immunised and control cattle were similar and all infected cattle died. It is suggested that the failure of BCG to protect cattle against T parva infection is because the cattle ...
T T, Dolan, C G, Brown, M P, Cunningham
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A Theileria parva type 1 protein phosphatase activity

Molecular and Biochemical Parasitology, 2000
The protozoan parasite Theileria (spp. parva and annulata) infects bovine leukocytes and provokes a leukaemia-like disease in vivo. In this study, we have detected a type 1 serine/threonine phosphatase activity with phosphorylase a as a substrate, in protein extracts of parasites purified from infected B lymphocytes. In contrast to this type 1 activity,
Cayla, Xavier   +4 more
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Bulk-freezing of Theileria parva stabilates for vaccine production

International Journal for Parasitology, 1996
The freezing and thawing characteristics of different volume samples of freezing medium and Theileria parva stabilates were studied in order to identify suitable conditions for freezing large volumes of stabilates for use in the preparation of vaccines.
L M, Njuguna, F L, Musisi
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Dose dependent responses of cattle to Theileria parva stabilate

International Journal for Parasitology, 1984
Abstract Dolan T. T. , Young A.S. , Losos G.J. , McMillan I. , Minder Ch.E. and Soulsby K. 1984. Dose dependent responses of Theileria parva stabilate. International Journal for Parasitology14: 89–95. A tick derived stabilate of Theileria parva (Maguga) was titrated in a large group of Boran (Bos indicus) cattle of the same age, sex and ...
T T, Dolan   +5 more
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