Results 61 to 70 of about 14,799 (201)

Integrative Genomics Identifies Candidate Genes Underlying Trypanotolerance in Hybrid African Cattle

Evolutionary Applications, Volume 19, Issue 6, June 2026.
ABSTRACT Integrative genomics combines data from different omics sources to link genotypes and phenotypes with the aim of unravelling biological networks and pathways that undergird complex traits, particularly with respect to disease. In this respect, integrative genomics, leveraging population and functional genomic data, can be employed to ...
Gillian P. McHugo, James A. Ward, Said Ismael Ng'ang'a, Laurent A. F. Frantz, John A. Browne, Michael Salter‐Townshend, Grace M. O'Gorman, Kieran G. Meade, Emmeline W. Hill, Thomas J. Hall, David E. MacHugh   +10 more
wiley   +1 more source

Theileria annulata and T. parva infect and transform different bovine mononuclear cells [PDF]

, 1989
Bovine peripheral blood mononuclear cells (PBMC) were labelled with monoclonal antibodies recognizing bovine MHC class II, sIgM, monocyte, T-helper and T-cytotoxic cell phenotypes.
Brown, C G, Innes, E A, Spooner, R L, Glass, E J   +3 more
core  

Induction of humoral immune response to multiple recombinant Rhipicephalus appendiculatus antigens and their effect on tick feeding success and pathogen transmission [PDF]

, 2016
BACKGROUND: Rhipicephalus appendiculatus is the primary vector of Theileria parva, the etiological agent of East Coast fever (ECF), a devastating disease of cattle in sub-Saharan Africa.
Scoles, Glen A., Stephen Mwaura, Odongo, David O., Glen A. Scoles, David O. Odongo, Olds, Cassandra L., David Odongo (3497480), Richard Bishop (59737), Richard Bishop, Claudia Daubenberger (212658), Glen Scoles (3448283), Daubenberger, Claudia, Stephen Mwaura (3485219), Bishop, Richard, Cassandra L. Olds, Mwaura, Stephen, Claudia Daubenberger, Cassandra Olds (3485216)   +17 more
core   +1 more source

East Coast Fever Caused by Theileria parva Is Characterized by Macrophage Activation Associated with Vasculitis and Respiratory Failure.

PLoS ONE, 2016
Respiratory failure and death in East Coast Fever (ECF), a clinical syndrome of African cattle caused by the apicomplexan parasite Theileria parva, has historically been attributed to pulmonary infiltration by infected lymphocytes.
Lindsay M Fry, David A Schneider, Charles W Frevert, Danielle D Nelson, W Ivan Morrison, Donald P Knowles   +5 more
doaj   +1 more source

Molecular Investigation of Tick-Borne Haemoparasites Isolated from Indigenous Zebu Cattle in the Tanga Region, Tanzania

Animals, 2022
Tick-borne diseases (TBDs) are a major hindrance to livestock production in pastoral communities of Africa. Although information on tick-borne infections is necessary for setting up control measures, this information is limited in the pastoral ...
Aaron Edmond Ringo, Hezron Emanuel Nonga, Eloiza May Galon, Shengwei Ji, Mohamed Abdo Rizk, Shimaa Abd El-Salam El-Sayed, Uday Kumar Mohanta, Zhuowei Ma, Boniface Chikufenji, Thanh Thom Do, Xuenan Xuan   +10 more
doaj   +1 more source

Two Decades of Global Research Trends on Major Histocompatibility Complex Class I Gene on Farm Animals: Bibliometric Analysis (2001 to 2020)

Veterinary Medicine and Science, Volume 12, Issue 2, March 2026.
In this study, a bibliometric mapping of two decades (2001–2020) of literature on the Major Histocompatibility Complex Class I (MHCI) gene in farm animals was conducted. The analysis revealed that research topics such as ‘Animals’ and ‘Major Histocompatibility Antigen Class I’ were trending, with the USA and UK contributing the highest publication ...
Masixole Maswana, Dikeledi Petunia Malatji, Thobela Louis Tyasi   +2 more
wiley   +1 more source

Molecular epidemiology of Theileria parva in the field

Tropical Medicine & International Health, 1999
Summary Molecular tools based on seminested RFLP‐PCR techniques to characterize field parasites in bloodspots dried on filter paper permitted investigation of the extent and the dynamics of diversity of Theileria parva populations in the field. Parallel molecular studies explored the long‐term genome stability of various isolates by probing Southern ...
Geysen, D., Bishop, Richard P., Skilton, Robert A., Dolan, T.T., Morzaria, S.P.   +4 more
openaire   +3 more sources

Modulation of NF-kappaB activation in Theileria annulata-infected cloned cell lines is associated with detection of parasite-dependent IKK signalosomes and disruption of the actin cytoskeleton [PDF]

, 2010
Apicomplexan parasites within the genus <i>Theileria</i> have the ability to induce continuous proliferation and prevent apoptosis of the infected bovine leukocyte.
Weir, W., Hermann, P., McKellar, S., Dobbelaere, D., Dobbelaere, Dirk,, Schmuckli-Maurer, J., Pillai, S., Shiels, B., Kinnaird, J.   +8 more
core   +1 more source

Organisation and informational content of the Theileria parva genome

Molecular and Biochemical Parasitology, 1998
When compared with other Apicomplexan organisms, Theileria parva has an exceptionally small, 10-12 Mbp, genome. There are only 4 chromosomes, each in the Mbp range, and a complete physical map, based on SfiI linking data, is available for each one. A number of genes and cDNAs have been mapped to specific SfiI fragments.
Nene, Vishvanath, Morzaria, S.P., Bishop, Richard P.   +2 more
openaire   +3 more sources

Spatial Heterogeneity of Tick‐Borne Pathogens Outpaces Genetic Structuring in Anatolian Dermacentor reticulatus Populations

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Understanding how vector population structure influences pathogen circulation remains a major challenge in tick‐borne disease ecology, particularly in biogeographically transitional regions. Dermacentor reticulatus, a widespread Palearctic tick species and vector of multiple pathogens, provides a useful system to investigate this relationship in a ...
Ömer Orkun, Maide Nur Gündoğdu, Tuğba Özdemir, Mesut Yiğit, Barış Yıldız, Ahmet Deniz, Zati Vatansever, Yong-guo Cao   +7 more
wiley   +1 more source