Results 51 to 60 of about 26,299,238 (255)

The clinical-stage drug BTZ-043 accumulates in murine tuberculosis lesions and efficiently acts against Mycobacterium tuberculosis

Nature Communications
The development of granulomas with central necrosis harboring Mycobacterium tuberculosis (Mtb) is the hallmark of human tuberculosis (TB). New anti-TB therapies need to effectively penetrate the cellular and necrotic compartments of these lesions and ...
Andreas Römpp, Axel Treu, Julia Kokesch-Himmelreich, Franziska Marwitz, Julia Dreisbach, Nadine Aboutara, Doris Hillemann, Moritz Garrelts, Paul J. Converse, Sandeep Tyagi, Sina Gerbach, Luzia Gyr, Ann-Kathrin Lemm, Johanna Volz, Alexandra Hölscher, Leon Gröschel, Eva-Maria Stemp, Norbert Heinrich, Florian Kloss, Eric L. Nuermberger, Dominik Schwudke, Michael Hoelscher, Christoph Hölscher, Kerstin Walter   +23 more
doaj   +1 more source

Right to media: breaking Indigenous Peoples’ systemic isolation

Frontiers in Communication
Representation of the world’s Indigenous Peoples’ cultural, political, environmental, and social issues continues to be marginalized within and across the seven sociocultural regions designated by the UNPFII (Africa, the Arctic, Asia, Central and South ...
Reynaldo A. Morales, Reynaldo A. Morales, Reynaldo A. Morales, Zella B. Milfred   +3 more
doaj   +1 more source

Supporting best practice in reflexive thematic analysis reporting in Palliative Medicine: A review of published research and introduction to the Reflexive Thematic Analysis Reporting Guidelines (RTARG)

Palliative Medicine
Background: Reflexive thematic analysis is widely used in qualitative research published in Palliative Medicine, and in the broader field of health research. However, this approach is often not used well.
Virginia Braun, Victoria Clarke
semanticscholar   +1 more source

Performing an Inductive Thematic Analysis of Semi-Structured Interviews With a Large Language Model: An Exploration and Provocation on the Limits of the Approach

Social science computer review, 2023
Large Language Models (LLMs) have emerged as powerful generative Artificial Intelligence solutions. This paper presents results and reflections of an experiment done with the LLM GPT 3.5-Turbo to perform an inductive Thematic Analysis (TA).
Stefano De Paoli
semanticscholar   +1 more source

Determining Parental Factors for Clinical Trial Attrition in Pediatric Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background/Objectives Despite high enrollment rates on Children's Oncology Group (COG) protocols, attrition after initial consent is challenging, introducing bias and prolonging trial completion. While adult oncology literature has identified predictors of withdrawal, little is known about caregiver decision‐making for child participation in ...
Kimberly L. Stathas, Jakob Q. Weiss, Kellee N. Parker, Cathy Lee‐Miller   +3 more
wiley   +1 more source

Methane yield response to pretreatment is dependent on substrate chemical composition: a meta-analysis on anaerobic digestion systems

Scientific Reports
Proper pretreatment of organic residues prior to anaerobic digestion (AD) can maximize global biogas production from varying sources without increasing the amount of digestate, contributing to global decarbonization goals.
Thuane Mendes Anacleto, Betina Kozlowsky-Suzuki, Annika Björn, Sepehr Shakeri Yekta, Laura Shizue Moriga Masuda, Vinícius Peruzzi de Oliveira, Alex Enrich-Prast   +6 more
doaj   +1 more source

Impact of Japan's 2024 Physician Work‐Style Reform on Pediatric Hematology–Oncology: Educational Implications in a 2‐Year Survey

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Japan's 2024 physician work‐style reform introduced legally binding limits on physicians’ working hours, but its impact on education and workforce sustainability in pediatric hematology–oncology (PHO) remains unclear. Procedure We conducted a repeated cross‐sectional study with structured quantitative items and free‐text responses ...
Kiyohiko Kaizu, Masaharu Akiyama, Toshikazu Itabashi, Jun Hayakawa, Takahiro Kikuchi, Ryohei Fukunaga, Katsuyoshi Koh, Takahiro Ueda   +7 more
wiley   +1 more source

Why I left and why I want to leave; A Phenomenological Perspective of Asian Employees Turnover

International Journal of Experiential Learning & Case Studies, 2022
The current research was conducted to explore the possible causes of actual employee turnover and turnover intentions. Using Post positivism research philosophy, phenomenological qualitative research method was used to explore the phenomena.
Metab Abbass Kazi, Naveed Anwer, Jahngeer Lakho, Abbass Kazi   +3 more
doaj   +1 more source

Infant Embryonal CNS Tumors: Molecular Insights and Treatment Considerations for Contemporary Pediatric Neuro‐Oncology

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Embryonal tumors comprise the majority of malignant central nervous system (CNS) neoplasms diagnosed in children under 3 years of age. Compared with their counterparts in older children, these tumors exhibit distinct molecular biology and a more aggressive clinical phenotype, while their management is complicated by the heightened ...
Sudarshawn Damodharan, Mariah Wright‐Nadkarni, Mohamed S. Abdelbaki, Girish Dhall   +3 more
wiley   +1 more source

Hermeneutic Thematic Analysis: Anchoring Thematic Analysis in Hermeneutic Philosophy

International Journal of Qualitative Methods
Thematic analysis (TA) is widely used in qualitative research, but its methodological flexibility has also led to inconsistent integration of hermeneutic principles.
Linda S. Estman
doaj   +1 more source