Results 51 to 60 of about 22,518,336 (272)

The clinical-stage drug BTZ-043 accumulates in murine tuberculosis lesions and efficiently acts against Mycobacterium tuberculosis

open access: yesNature Communications
The development of granulomas with central necrosis harboring Mycobacterium tuberculosis (Mtb) is the hallmark of human tuberculosis (TB). New anti-TB therapies need to effectively penetrate the cellular and necrotic compartments of these lesions and ...
Andreas Römpp   +23 more
doaj   +1 more source

Right to media: breaking Indigenous Peoples’ systemic isolation

open access: yesFrontiers in Communication
Representation of the world’s Indigenous Peoples’ cultural, political, environmental, and social issues continues to be marginalized within and across the seven sociocultural regions designated by the UNPFII (Africa, the Arctic, Asia, Central and South ...
Reynaldo A. Morales   +3 more
doaj   +1 more source

A Thematic Analysis of Mental Illness in New Zealand News Articles [PDF]

open access: yes, 2014
Mental illness is one of the main reasons for disability in the western world with one in five individuals being classed as mentally ill during some time in their life.
Fernandez, Brett
core  

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

open access: yesMolecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu   +3 more
wiley   +1 more source

Methane yield response to pretreatment is dependent on substrate chemical composition: a meta-analysis on anaerobic digestion systems

open access: yesScientific Reports
Proper pretreatment of organic residues prior to anaerobic digestion (AD) can maximize global biogas production from varying sources without increasing the amount of digestate, contributing to global decarbonization goals.
Thuane Mendes Anacleto   +6 more
doaj   +1 more source

Preserved thematic and impaired taxonomic categorisation: a case study [PDF]

open access: yes, 2004
The present paper seeks to understand more about categorisation and its relation to naming. A patient with language impairments (LEW) was examined in a three-part investigation of his ability to make classification decisions.
Davidoff, Jules B.   +3 more
core   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

Optimal Thematic Interpretation [PDF]

open access: yes, 2002
Vogel R. Optimal Thematic Interpretation. Presented at the 2nd International Conference on Construction Grammar.The paper argues with the example of polyvalent verbs that mechanisms of argument linking and constructional fusion as assumed in construction
Vogel, Ralf ; https://orcid.org/
core  

Perceived processes of art therapy for adults experiencing psychosis: a reflexive thematic analysis [PDF]

open access: yes, 2020
Section A This review aimed to explore how service users with psychosis diagnoses experience arts therapies. Online databases including PsycInfo, Medline, and Social Policy and Practice were searched, yielding thirteen papers. The findings suggest most
Barrett, H.
core  

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

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