Results 71 to 80 of about 26,299,238 (255)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Thematic-LM: A LLM-based Multi-agent System for Large-scale Thematic Analysis

open access: yesThe Web Conference
Thematic analysis (TA) is a widely used qualitative method for identifying underlying meanings within unstructured text. However, TA requires manual processes, which become increasingly labour-intensive and time-consuming as datasets grow.
Tingrui Qiao   +3 more
semanticscholar   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Augmented reality applications: A Meta-analysis and thematic analysis

open access: yesTurkish Journal of Education, 2019
The purpose of this study is to determine the effect of augmented reality (AR) applications on academic success through meta-analytic and thematic analysis. 51 items from 45 studies conducted between 2013 and 2019 were examined in different databases on
Veli Batdı, Tarık Talan
doaj   +1 more source

Thematic analysis in the area of education: a practical guide

open access: yesCogent Education
This paper addresses the growing popularity of thematic analysis (TA) in education research and the lack of a comprehensive guide tailored specifically for this field.
Iryna Kushnir
semanticscholar   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

open access: yesMolecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu   +3 more
wiley   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

An integrated guide to thematic analysis

open access: yesJournalistica
In this section, Journalistica puts a spotlight on research methods used in journalism studies and/or journalism practice.
Miriam Kroman Brems   +1 more
doaj   +1 more source

Qualitative analysis of factors that increase and reduce involvement in gambling

open access: yesSocialinis Darbas: Patirtis ir Metodai, 2015
During the rapid development of gambling business, the number of pathological gamblers is increasing as well. The problem of pathological gambling is just as important as alcoholism or drug addiction.
Egidijus , Meiženis
doaj   +1 more source

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