Results 91 to 100 of about 2,665,540 (305)

What are incremental themes? [PDF]

open access: yes, 2013
In this paper I examine the approach to incremental themes developed in Krifka 1992,1998, Dowty 1991 and others, which argues that the extent of a telic event is determined by the extent of its incrementally affected theme.
Rothstein, Susan Deborah
core  

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Куба в творчестве художника Владимира Ивановича Переяславца (1918–2018)

open access: yesИскусство Евразии
В статье рассматривается творчество Владимира Ивановича Переяславца, дается краткий анализ его произведений, посвященных Кубе. Художник студии военных художников имени М. Грекова, участник Великой Отечественной войны, В.И.
Мушникова, Е.А.
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

THE SONATA FOR VIOLIN AND PIANO BY VIOREL MUNTEANU IN THE INTERPRETATIVE CONCEPTION OF NATIVE MUSICIANS [PDF]

open access: yesStudiul Artelor şi Culturologie: Istorie, Teorie, Practică, 2016
Signed in 1974, the Sonata for violin and piano by Viorel Munteanu continues the Enescu tradition and distinguishes itself by an original musical language, that alongside of the form sobriety, places this opus among the most representative examples of ...
STOLEARCIUC XENIA
doaj  

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

MAJOR THEMES IN OUR FOREIGN POLICY [PDF]

open access: yes
International Relations/Trade,
Popper, David H.
core   +1 more source

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