Results 81 to 90 of about 85,619 (248)

DIMETILSULFOKSID SEBAGAI ENHANCER TRANSPOR TRANSDERMAL TEOFILIN SEDIAAN GEL

Pharmaciana, 2013
Dimethylsulfoxide (DMSO) has been intensively studied the 19th century. This substance is used as a medicine and solve. It can also be used as an absorption enhancer of various drugs, either synthetical or herbal medicines.
Resty Annisa Damayanti, Tedjo Yuwono
doaj   +1 more source

Cell‐Type‐Specific WTAP and ALKBH5‐Mediated m6A Methylation Orchestrates Mental Disorders via Gut‐Brain Axis Metabolite Signaling: Multi‐Omics Evidence and Pyroptosis‐Associated Loop Mechanism

CNS Neuroscience &Therapeutics, Volume 32, Issue 3, March 2026.
MR analysis revealed distinct causal associations of m6A modifiers (WTAP/ALKBH5) with mental disorders. Gut microbiota (GCA‐900066755, Bacillus) and CSF metabolites (theophylline, isoleucine) mediated 5.06%–45.28% of effects via pathways such as WTAP → GCA‐900066755 → theophylline → ADHD. Single‐cell eQTL linked WTAP‐mediated ADHD risk to XCL1‐NK cells,
Jingjing Zhang, Xue Liu, Xiaoming Liu, Liqun Zhao, Junjie Bi   +4 more
wiley   +1 more source

Kinetic study of peroxidase enzyme in the presence of purine alkaloids

یافته‌های نوین در علوم زیستی, 2022
Peroxidase catalyzes different oxidation of substrates using hydrogen peroxide, a reactive oxygen specie (ROS). ROS, at low concentrations, act as messenger to regulate intracellular signaling, whereas, at high concentrations, they can overcome the ...
Tayyebeh Rahmati darvazi, Reyhaneh Sariri   +1 more
doaj  

Open Systems Pharmacology Community Conference (OSP‐CC) Proceedings 2025

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 3, March 2026.
ABSTRACT Developed at Bayer Technology Services, PK‐Sim and MoBi transitioned into the Open Systems Pharmacology (OSP) Suite, released as free open‐source software in 2017. An active community with stakeholders from academia, industries, and regulators contributes to the continuous improvement of open‐source model‐informed drug development (MIDD). This
Henrik Cordes, Pieter Annaert, Pavel Balazki, Salih Benamara, Rodolfo Hernandes Bonan, Andrew Butler, Marylore Chenel, Yunhai Cui, André Dallmann, Wilhelmus E. A. de Witte, Cleo Demeester, Denise Feick, Florence Gattacceca, René Geci, Grégori Gerebtzoff, Andrea Gruber, Mariana Guimarães, Abdullah Hamadeh, Nina Hanke, Manuel Ibarra, Ibrahim Ince, Tobias Kanacher, Lars Kuepfer, Felix Mil, Ghazal Montaseri, Nina Nauwelaerts, Susana Proenca, Stephan Schaller, Jan Frederik Schlender, Annika R. P. Schneider, Erik Sjögren, Juri Solodenko, Alexander Staab, Paul Vrenken, Carla Troisi, Donato Teutonico   +35 more
wiley   +1 more source

Pharmacokinetic Herb-Drug Interactions: Insight into Mechanisms and Consequences [PDF]

, 2015
Herbal medicines are currently in high demand, and their popularity is steadily increasing. Because of their perceived effectiveness, fewer side effects and relatively low cost, they are being used for the management of numerous medical conditions ...
Horie, Toshiharu, Oga, Enoche Florence, Sekine, Shuichi, Shitara, Yoshihisa   +3 more
core   +1 more source

Study on Effectiveness of Low Dose Theophylline as Add-on to Inhaled Corticosteroid for Patients with Sulfur Mustard Induced Bronchiolitis [PDF]

Asia Pacific Journal of Medical Toxicology, 2013
Background: Theophylline may reverse steroid resistance and decrease inflammation in patients with chronic pulmonary disease and sulfur mustard (SM) induced bronchiolitis.
Yunes Panahi, Zohreh Poursaleh, Ali Amini-Harandi, Amin Saburi, Majid Shohrati, Mostafa Ghanei   +5 more
doaj  

Cord Blood Theophylline Levels and Respiratory Morbidities In Preterm Infants

Gynecology Obstetrics & Reproductive Medicine, 2019
Objective: to investigate whether there is any relationship between cord blood theophylline levels and pulmonary morbidities in the early neonatal period in premature infants.
Tolga Hasan Celik, Ayse Korkmaz, Sule Yigit, Murat Yurdakok   +3 more
doaj   +1 more source

Coumarins and Their Derivatives in Animal Models of Asthma: A Systematic Review

Basic &Clinical Pharmacology &Toxicology, Volume 138, Issue 3, March 2026.
Mast cells drive early allergic asthma by releasing histamine, interleukins and prostaglandins, causing airway hyperresponsiveness, mucus overproduction and inflammation. These events sustain symptoms and promote structural remodelling, contributing to the progression of the disease.
Iêda Maria dos Santos, João Lázaro de Oliveira Rocha, Edilson Beserra de Alencar Filho, Fabrício Souza Silva   +3 more
wiley   +1 more source

Adsorption Isotherms of Caffeine and Theophylline on Metal-Organic Frameworks

Adsorption Science & Technology, 2014
The adsorption behaviours of caffeine and theophylline on different metal-organic frameworks were examined by comparing their adsorption isotherms. Among C 18 , UIO-66, UIO-66-NH 2 and MIL-125-NH 2 , UIO-66 showed the highest amount of adsorption of ...
Yu Ri Lee, Minglei Tian, Se-Na Kim, Wha-Seung Ahn, Kyung Ho Row   +4 more
doaj   +1 more source

Small Airway Function as an Indicator for Persistent Airflow Limitation Asthma: A Retrospective Study

The Clinical Respiratory Journal, Volume 20, Issue 3, March 2026.
ABSTRACT Background Asthma is a heterogeneous disease characterized by chronic inflammatory changes in the airways and reversible airflow limitation. Persistent airflow limitation (PAL) asthma, as a common phenotype of asthma, is usually defined as forced expiratory volume in 1 s/forced vital capacity (FEV1/FVC) ratio lower than 0.7 after ...
Zhongzhao Wang, Xintong Du, Yang Luo, Heng Gong, Hao Tang   +4 more
wiley   +1 more source