Results 81 to 90 of about 55,199 (226)

Population Pharmacokinetics of Sildenafil in Dogs With Naturally Occurring Pulmonary Hypertension

Journal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT The pharmacokinetics of sildenafil are ill‐defined in dogs with naturally occurring pulmonary hypertension (PH). Because the plasma concentrations of sildenafil have not been reported for dogs with this disease, this study aimed to describe the population pharmacokinetics of sildenafil in a sample of dogs with PH. Twenty client‐owned dogs with
Mariko Yata, Teresa C. DeFrancesco, John D. Bonagura, Mark G. Papich   +3 more
wiley   +1 more source

Study on Effectiveness of Low Dose Theophylline as Add-on to Inhaled Corticosteroid for Patients with Sulfur Mustard Induced Bronchiolitis [PDF]

Asia Pacific Journal of Medical Toxicology, 2013
Background: Theophylline may reverse steroid resistance and decrease inflammation in patients with chronic pulmonary disease and sulfur mustard (SM) induced bronchiolitis.
Yunes Panahi, Zohreh Poursaleh, Ali Amini-Harandi, Amin Saburi, Majid Shohrati, Mostafa Ghanei   +5 more
doaj  

Adsorption Isotherms of Caffeine and Theophylline on Metal-Organic Frameworks

Adsorption Science & Technology, 2014
The adsorption behaviours of caffeine and theophylline on different metal-organic frameworks were examined by comparing their adsorption isotherms. Among C 18 , UIO-66, UIO-66-NH 2 and MIL-125-NH 2 , UIO-66 showed the highest amount of adsorption of ...
Yu Ri Lee, Minglei Tian, Se-Na Kim, Wha-Seung Ahn, Kyung Ho Row   +4 more
doaj   +1 more source

Design principles for riboswitch function [PDF]

, 2009
Scientific and technological advances that enable the tuning of integrated regulatory components to match network and system requirements are critical to reliably control the function of biological systems. RNA provides a promising building block for the
A Belle, A Levchenko, A Zaslaver, Adam P. Arkin, B Suess, B Suess, CA Voigt, Chase L. Beisel, Christina D. Smolke, CI An, CL Beisel, DH Mathews, DJ Klein, DM Crothers, DW Selinger, E Dekel, FJ Isaacs, FJ Isaacs, GJ Leclerc, GM Emilsson, GM Suel, GR Zimmermann, HM Al-Hashimi, J Tomsic, JA Bernstein, JA Collins, JE Barrick, JF Lemay, JK Wickiser, JK Wickiser, K Lang, LJ Su, LV Danilova, M Acar, M Parisien, MN Win, MN Win, MR Bennett, MT Cheah, MT Woodside, N Hao, O Kensch, P Corish, PP Zarrinkar, PT Li, R Narsai, R Rieder, RD Jenison, RR Breaker, S Topp, S Topp, SA Lynch, SE Osborne, SK Desai, T Pan, TH Lee, TS Bayer, WC Winkler, WC Winkler, WJ Greenleaf, X Zhang, X Zhuang, Y Yokobayashi   +62 more
core   +4 more sources

The effects of a (poly)phenol‐rich food intervention on markers of exercise‐induced inflammation and oxidative stress: A randomised controlled trial

Experimental Physiology, EarlyView.
Abstract This study examined whether consuming a (poly)phenol‐rich food before strenuous muscle‐damaging exercise can modify post‐exercise markers of inflammation and oxidative stress. Using a double‐blinded, randomised, placebo‐controlled, between‐subjects design, 26 recreationally active males (n = 15) and females (n = 11) consumed higher‐(poly ...
Abrar Al Hebshi, Josh Thorley, Ana Rodriguez‐Mateos, Zicheng Zhang, Lewis J James, Tom Clifford   +5 more
wiley   +1 more source

Expert Opinion on Controlled-release Theophylline as an Add-on Therapy in the Management of Chronic Obstructive Pulmonary Disease and Asthma

Journal of Advanced Lung Health
In India, asthma and chronic obstructive pulmonary disease (COPD) are leading chronic respiratory disorders that play a major role in causing morbidity and mortality.
Pralhad Prabhudesai, Agam Vora, Subramanyam Raju, Prashant Chhajed, Samir Garde, Shailesh Jain, Sandeep Tilve, Dharmendra Dubey, Kamleshkumar Pandey, Pankaj Bang, Sumit Goyal   +10 more
doaj   +1 more source

Kinetic study of peroxidase enzyme in the presence of purine alkaloids

یافته‌های نوین در علوم زیستی, 2022
Peroxidase catalyzes different oxidation of substrates using hydrogen peroxide, a reactive oxygen specie (ROS). ROS, at low concentrations, act as messenger to regulate intracellular signaling, whereas, at high concentrations, they can overcome the ...
Tayyebeh Rahmati darvazi, Reyhaneh Sariri   +1 more
doaj  

Maternal nutrition as a key determinant of placental and developing blood–brain barrier xenobiotic protective functions

The Journal of Physiology, EarlyView.
Abstract figure legend Suboptimal maternal nutrition alters placental and developing blood–brain barrier (BBB) protective function and is associated with increased fetal brain vulnerability. In the placenta, nutritional adversity may reduce the exchange surface area and promote meta‐inflammation, compromising barrier efficiency in a model‐ and context ...
Kristin L. Connor, Nycolle I. S. Souza, Bruno G. Anjos, Stephen G. Matthews, Enrrico Bloise   +4 more
wiley   +1 more source

Efficacy and side effects of intravenous theophylline in acute asthma: a systematic review and meta-analysis

Drug Design, Development and Therapy, 2018
Gulixian Mahemuti, Hui Zhang, Jing Li, Nueramina Tieliwaerdi, Lili Ren Respiratory Department, The Second Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang Province, People’s Republic of China Background and objective ...
Mahemuti G, Zhang H, Li J, Tieliwaerdi N, Ren L   +4 more
doaj  

Factors associated with potentially inappropriate medication use, medication underuse and overuse in older adults in the German National Cohort

Journal of Internal Medicine, Volume 299, Issue 6, Page 754-775, June 2026.
Abstract Background Effectively identifying individuals exposed to drug underuse, overuse and potentially inappropriate medication (PIM) in older adults is essential for minimizing preventable drug‐related harms. Methods We analysed data from 54,296 individuals aged 60–74 years from the German National Cohort (NAKO).
Miriam Degen, Ulrike Haug, Oliver H. F. Scholle, Yaw Awuku‐Larbi, Sigrid Carlsson, Nina Ebert, Volker Harth, Anja M. Hauri, Margit Heier, Anne Herrmann, Michael Leitzmann, Jakob Linseisen, Claudia Meinke‐Franze, Nadia Obi, Phil Pendt, Thomas Reinhold, Barbara Thorand, Hermann Brenner, Ben Schöttker   +18 more
wiley   +1 more source