Results 51 to 60 of about 1,819,221 (292)
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Theoretical Study of Quercetin Derivatives
Journal of New Results in Science, 2019 Kuesetin,birçok bitkiden izole edilen, çok sayıda biyolojik aktivite gösteren önemli birdoğal üründür. Doğal ürünler, formakolojik etkilerini güçlendirmek içinfoksiyonel hale getirilir.
Ramazan Erenler, Faik Gokalp
doaj
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
The Distribution Law of Floor Fracture Zone of No.16 Coal Mining Face in Limin Coal Mine
Meikuang Anquan, 2020 To avoid the water inrush from the floor of the working face, according to the characteristics of large mining height and long working face of 1603 first mining face of 16 coal above Ordovician limestone in Limin Mine, theoretical calculation and ...
LIU Dongming
doaj +1 more source
Theoretical Calculations on Solid Argon [PDF]
Nature, 1956 IT is well known that a knowledge of the second virial coefficient of a gas does not suffice to specify the intermolecular potential of the constituent molecules. In fact, even if a simple formula of Mie–Lennard-Jones type is used as an approximation to the potential, the parameters are not uniquely determined by the second virial coefficient.
C. DOMB, I. J. ZUCKER
openaire +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Radiative Corrections to Chargino Production in Electron-Positron Collisions
, 2000 The results of a complete one-loop calculation for the production of chargino pairs in electron-positron collisions, including the option of polarized beams, are presented.
Blank, T., Hollik, W.
core +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
BuildingsOne of the important directions for green development in the world today is to expand the application methods of recycled concrete, improve the utilization rate of waste aggregates, and slow down the consumption of natural resources. The column structure
Jianchao Wang, Huayu Li, Wei Hou
doaj +1 more source
, 2004 A precise determination of the W boson mass at the Fermilab Tevatron requires a theoretical calculation in which the effects of the initial-state multiple soft-gluon emission and the final-state photonic correction are simultaneously included .
Cao, Qing-Hong, Yuan, C. -P.
core +1 more source