Results 61 to 70 of about 1,793,343 (326)

SYMMETRIC AND ASYMMETRIC RAMSEY PROPERTIES IN RANDOM HYPERGRAPHS

Forum of Mathematics, Sigma, 2017
A celebrated result of Rödl and Ruciński states that for every graph $F$ , which is not a forest of stars and paths of length 3, and fixed number of colours
LUCA GUGELMANN, RAJKO NENADOV, YURY PERSON, NEMANJA ŠKORIĆ, ANGELIKA STEGER, HENNING THOMAS   +5 more
doaj   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Fast learning without synaptic plasticity in spiking neural networks

Scientific Reports
Spiking neural networks are of high current interest, both from the perspective of modelling neural networks of the brain and for porting their fast learning capability and energy efficiency into neuromorphic hardware. But so far we have not been able to
Anand Subramoney, Guillaume Bellec, Franz Scherr, Robert Legenstein, Wolfgang Maass   +4 more
doaj   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Exploiting the structure effectively and efficiently in low rank matrix recovery

, 2018
Low rank model arises from a wide range of applications, including machine learning, signal processing, computer algebra, computer vision, and imaging science.
Absil, Agarwal, Ahmed, Alter, Amelunxen, Beck, Blanchard, Blumensath, Boumal, Boyd, Bunk, Cai, Cai, Cai, Cai, Cai, Cai, Candes, Candes, Candes, Candes, Candes, Candès, Candès, Candès, Candès, Carmon, Chandrasekaran, Chen, Chen, Chen, Chen, Chen, Chen, Chen, Chen, Chen, Combettes, Davenport, Davenport, Ding, Donoho, Fazel, Ge, Ge, Ge, Goldberg, Gross, Hardt, Harrison, Huang, Jaggi, Jain, Jain, Ji, Jin, Keshavan, Kim, Kliesch, Koltchinskii, Krim, Kueng, Lanman, Li, Li, Lin, Ling, Ling, Liu, Liu, Lustig, Ma, Miao, Mishra, Mishra, Mishra, Mobahi, Mu, Negahban, Netrapalli, Ngo, Potter, Qu, Recht, Recht, Schermelleh, Srebro, Strohmer, Sun, Sun, Tanner, Tanner, Tao, Tharrault, Toh, Toh, Tomasi, Tu, Vandereycken, Wang, Wei, Wei, Wei, Wen, WenHuang, Xu, Yi, Zhang, Zhang, Zheng   +109 more
core   +2 more sources

Quantum Applications In Political Science [PDF]

, 2020
Undergraduate Research ScholarshipThis paper will show the current state of quantum computation and its application as a political science research method.
Costa, Caleb
core  

Microfluidic electro‐viscoelastic manipulation of extracellular vesicles

FEBS Open Bio, EarlyView.
The electro‐viscoelastic manipulation as a potential method for separation of particles based on size. The particles introduced as a sheath flow migrate to the channel center under the influence of simultaneously applied electric field and pressure driven flow.
Seyedamirhosein Abdorahimzadeh, Éva Bozó, Zikrullah Bölükkaya, Artem Zhyvolozhnyi, Anatoliy Samoylenko, Henrikki Liimatainen, Seppo J. Vainio, Caglar Elbuken   +7 more
wiley   +1 more source

A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms

FEBS Open Bio, EarlyView.
We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley   +1 more source

Homologous expression and purification of human HAX‐1 for structural studies

FEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

ORGANIZATION OF PEDAGOGICAL CONDITIONS COMPUTER AND INFORMATION TRAINING IN SYSTEM OF ADDITIONAL PROFESSIONAL EDICATION

Sovremennye Issledovaniâ Socialʹnyh Problem, 2016
The article presents the results of theoretical analysis of pedagogical researches of creating conditions of computer-learning using the information and the teaching materials on the basis of academic disciplines: social sciences and humanities and ...
Alexey Anatol’evich Oleynikov, Almira Aykaydarovna Mukasheva   +1 more
doaj   +1 more source