Results 61 to 70 of about 1,693,747 (308)

Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells

open access: yesFEBS Letters, EarlyView.
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan   +2 more
wiley   +1 more source

Lagrange Dual Method for Sparsity Constrained Optimization

open access: yesIEEE Access, 2018
In this paper, we investigate the l0 quasi-norm constrained optimization problem in the Lagrange dual framework and show that the strong duality property holds.
Wenxing Zhu   +3 more
doaj   +1 more source

Hamiltonian complexity

open access: yes, 2011
In recent years we've seen the birth of a new field known as hamiltonian complexity lying at the crossroads between computer science and theoretical physics.
Osborne, Tobias J.
core   +1 more source

Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes

open access: yesFEBS Letters, EarlyView.
Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley   +1 more source

NAPC: A Neural Algorithm for Automated Passenger Counting in Public Transport on a Privacy-Friendly Dataset

open access: yesIEEE Open Journal of Intelligent Transportation Systems, 2022
Real-time load information in public transport is of high importance for both passengers and service providers. Neural algorithms have shown a high performance on various object counting tasks and play a continually growing methodological role in ...
Robert Seidel   +4 more
doaj   +1 more source

New Trends in Quantum Computing

open access: yes, 1996
Classical and quantum information are very different. Together they can perform feats that neither could achieve alone, such as quantum computing, quantum cryptography and quantum teleportation.
Brassard, Gilles
core   +2 more sources

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

open access: yesMolecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani   +14 more
wiley   +1 more source

Fast learning without synaptic plasticity in spiking neural networks

open access: yesScientific Reports
Spiking neural networks are of high current interest, both from the perspective of modelling neural networks of the brain and for porting their fast learning capability and energy efficiency into neuromorphic hardware. But so far we have not been able to
Anand Subramoney   +4 more
doaj   +1 more source

Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte   +10 more
wiley   +1 more source

Association of high‐dose radioactive iodine therapy with PPM1D‐mutated clonal hematopoiesis in older individuals

open access: yesMolecular Oncology, EarlyView.
In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim   +11 more
wiley   +1 more source

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