Results 61 to 70 of about 1,761,622 (323)

Teaching computer programming: impact of Brown and Wilson's didactical principles

open access: yesFrontiers in Computer Science, 2023
This research studies the effects of the application of didactics to the teaching of computer programming, focusing on programming skills in the Python computer language.
Hector Belmar, Hector Belmar
doaj   +1 more source

Visions in Theoretical Computer Science: A Report on the TCS Visioning Workshop 2020 [PDF]

open access: green, 2021
Shuchi Chawla   +3 more
openalex   +1 more source

A unified model for Duchenne muscular dystrophy gene involvement in cancer: context‐dependent tumour suppression and oncogenicity

open access: yesFEBS Open Bio, EarlyView.
We propose a context‐dependent model where the Duchenne muscular dystrophy (DMD) gene acts as a tumour suppressor in aggressive tumours and as an oncogene in less aggressive ones. We propose this model as a unified framework to explain the opposing survival associations with DMD expression and to guide experimental exploration of the dual role of DMD ...
Lee Machado   +4 more
wiley   +1 more source

Diffusion‐based size determination of solute particles: a method adapted for postsynaptic proteins

open access: yesFEBS Open Bio, EarlyView.
We present a diffusion‐based approach for measuring the size of macromolecules and their complexes, and demonstrate its use on postsynaptic proteins. The method requires fluorescein‐labelled protein samples, a microfluidic device that maintains laminar flow for said samples, a microscope recording the emitted fluorescent signals, and an analytic ...
András László Szabó   +7 more
wiley   +1 more source

SYMMETRIC AND ASYMMETRIC RAMSEY PROPERTIES IN RANDOM HYPERGRAPHS

open access: yesForum of Mathematics, Sigma, 2017
A celebrated result of Rödl and Ruciński states that for every graph $F$ , which is not a forest of stars and paths of length 3, and fixed number of colours
LUCA GUGELMANN   +5 more
doaj   +1 more source

COMPUTER SCIENCE TEACHERS’ READINESS TO DEVELOP AND USE COMPUTER DIDACTIC GAMES IN EDUCATIONAL PROCESS

open access: yesІнформаційні технології і засоби навчання, 2020
The paper reports research on computer science teachers’ readiness to develop computer didactic games and implement them into the educational process. Today’s teacher of computer science has to acquire and improve professional competencies in line with ...
Роман Семенович Гуревич   +4 more
doaj   +1 more source

A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms

open access: yesFEBS Open Bio, EarlyView.
We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley   +1 more source

Fast learning without synaptic plasticity in spiking neural networks

open access: yesScientific Reports
Spiking neural networks are of high current interest, both from the perspective of modelling neural networks of the brain and for porting their fast learning capability and energy efficiency into neuromorphic hardware. But so far we have not been able to
Anand Subramoney   +4 more
doaj   +1 more source

Homologous expression and purification of human HAX‐1 for structural studies

open access: yesFEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

Exploiting the structure effectively and efficiently in low rank matrix recovery

open access: yes, 2018
Low rank model arises from a wide range of applications, including machine learning, signal processing, computer algebra, computer vision, and imaging science.
Absil   +109 more
core   +2 more sources

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