Results 41 to 50 of about 32,657,892 (281)

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Department of Computer Science newsletter 2022

open access: yes, 2022
A Newsletter for Friends and Supporters of the Mines Computer Science Department.

core  

Specifying computer-supported collaboration scripts [PDF]

open access: yes, 2007
Collaboration scripts are activity programs which aim to foster collaborative learning by structuring interaction between learners. Computer-supported collaboration scripts generally suffer from the problem of being restrained to a specific learning ...
Kobbe, Lars   +13 more
core   +1 more source

Lagrange Dual Method for Sparsity Constrained Optimization

open access: yesIEEE Access, 2018
In this paper, we investigate the l0 quasi-norm constrained optimization problem in the Lagrange dual framework and show that the strong duality property holds.
Wenxing Zhu   +3 more
doaj   +1 more source

Input Redundancy for Parameterized Quantum Circuits

open access: yesFrontiers in Physics, 2020
One proposal to utilize near-term quantum computers for machine learning are Parameterized Quantum Circuits (PQCs). There, input is encoded in a quantum state, parameter-dependent unitary evolution is applied, and ultimately an observable is measured. In
Francisco Javier Gil Vidal   +2 more
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Teaching computer programming: impact of Brown and Wilson's didactical principles

open access: yesFrontiers in Computer Science, 2023
This research studies the effects of the application of didactics to the teaching of computer programming, focusing on programming skills in the Python computer language.
Hector Belmar, Hector Belmar
doaj   +1 more source

A Theoretical Computer Science Perspective on Free Will

open access: yesCoRR, 2022
arXiv admin note: text overlap with arXiv:2107 ...
Lenore Blum, Manuel Blum 0001
openaire   +2 more sources

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