Results 31 to 40 of about 32,657,892 (281)
On the Descriptive Complexity of Color Coding
Algorithms, 2021 Color coding is an algorithmic technique used in parameterized complexity theory to detect “small” structures inside graphs. The idea is to derandomize algorithms that first randomly color a graph and then search for an easily-detectable, small color ...
Max Bannach, Till Tantau
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Why Using Robots to Teach Computer Science can be Successful Theoretical Reflection to Andragogy and Minimalism [PDF]
, 2008 Categories and Subject Descriptors K.3.1 [Computers and Education]: Computer Uses in Education – collaborative learning; K.3.2 [Computers and Education]: Computer and Information Science Education – computer science education, self-assessmentTo help ...
Kurhila, Jaakko +5 more
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Revista Brasileira de Ensino de Ciência e Tecnologia, 2021 This paper aims to understand the didactic formation of teachers/professors in IT and Computer Science from campus Colinas do Tocantins, of the Tocantins Federal Institute for Education, Science and Technology (IFTO).
Eliane Mittelstad Martins de Souza +3 more
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
The Era of Big Data Comes to Oceanography [PDF]
Oceanography, 2013 The late Jim Gray, who received the prestigious Turing Award in computer science and was a pioneer in the development of relational databases, proposed the "Fourth Paradigm" to describe the field of data-intensive science (Hey et al., 2009).
Mark R. Abbott
doaj +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
A Theoretical Computer Science Perspective on Consciousness
Journal of Artificial Intelligence and Consciousness, 2021 The quest to understand consciousness, once the purview of philosophers and theologians, is now actively pursued by scientists of many stripes. This paper studies consciousness from the perspective of theoretical computer science. It formalizes the Global Workspace Theory (GWT) originated by the cognitive neuroscientist Bernard Baars and further ...
Manuel Blum 0001, Lenore Blum
openaire +4 more sources
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Department of Computer Science newsletter Fall 2023
, 2023 A Newsletter for Friends and Supporters of the Mines Computer Science ...
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