Results 81 to 90 of about 5,813,746 (293)

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

FEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori, Kohei Kawabata, Takanori Kubo, Takeo Kitazawa, Sae Kanai, Madoka Iwashita, Ami Hayashi, Hiroyuki Nishi, Mikihisa Takano   +8 more
wiley   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Evaluating an integrated primary care approach to improve well-being among frail community-living older people: A theory-guided study protocol

BMC Geriatrics, 2018
Background A major challenge in primary healthcare is the substantial increase in the proportion of frail community-dwelling older persons with long-term conditions and multiple complex needs.
Lotte Vestjens, Jane M. Cramm, Erwin Birnie, Anna P. Nieboer   +3 more
doaj   +1 more source

Motivating Children and Adolescents in Obesity Treatment

Journal of Obesity & Metabolic Syndrome, 2020
Enhancing motivation is a crucial issue in pediatric obesity interventions, as behavioral changes related to food intake and physical exercise are difficult to carry out with an insufficient level of motivation.
Sarah Woo, Kyung Hee Park
doaj   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Un modelo explicativo de la conducta hacia la enfermedad mental An explanatory model of behavior towards mental illness

Salud Pública de México, 2002
Objetivo. Probar un modelo teórico diseñado para explicar las actitudes en relación con la enfermedad mental, a partir del conocimiento de las principales variables relacionadas con dicho constructo. Material y métodos.
Sarah García-Sílberman
doaj  

Understanding bio‐based polymers: A study of origins, properties, biodegradation and their impact on health and the environment

FEBS Open Bio, EarlyView.
This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc, Blaž Stres, Mirica Karlovits, Igor Karlovits, Petra Jerič, Ondrej Panák, Anja Verbič, Blaž Likozar, Uroš Novak   +8 more
wiley   +1 more source

THEORETICAL AND METHODOLOGICAL BACKGROUND TO THE DEVELOPMENT OF COUNTERCYCLICAL POLICY

Стратегические решения и риск-менеджмент, 2014
The theoretical model revealing the nature of cyclic processes in economy is constructed on the basis of the specified treatment of the interphase recurrence property concept.
О. V. Butorina
doaj   +1 more source

The effects of the nonextensivity on the dimerization process and nematic ordering

, 2003
The influence of the dimerization process on the nematic ordering is investigated by using a nonextensive thermostatistics, namely Tsallis thermostatistics(TT).
Antonova, Baldovin, Barbero, Beguin, Carr, Curado, de Gennes, Deloche, Frunza, Gruler, Humphries, Kayacan, Longa, Luckhurst, Montrucchio, O. Kayacan, Pershin, Petrov, Petrov, Petrov, Petrov, Petrov, Rao, Reis, Rondelez, Simova, Tsallis, Tsallis, Vertogen   +28 more
core   +1 more source