Results 91 to 100 of about 4,222,853 (324)

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

From adversity to adaptation: the struggle between resilience and athlete burnout in stressful situations

Frontiers in Psychology
Athlete burnout is considered a negative psychological consequence of stressors in sports, with the potential to adversely affect both the physical and mental well-being of athletes, as well as their overall performance. Resilience serves as a protective
Chenyi Cai, Zhengyang Mei, Yang Yang, Shi Luo   +3 more
doaj   +1 more source

Classical Cepheid Pulsation Models. III. The Predictable Scenario

, 1999
Within the current uncertainties in the treatment of the coupling between pulsation and convection, limiting amplitude, nonlinear, convective models appear the only viable approach for providing theoretical predictions about the intrinsic properties of ...
Alibert Y., Antonello E., Beaulieu J. P., Bersier D., Bersier D., Bersier D., Bono G., Butler C. J., Butler C. J., Castelli F., Castelli F., Coulson I. M., Fernie J. D., Fry A. M., Gascoigne S. C. B., Gascoigne S. C. B., Giuseppe Bono, Kienzle F., Kurucz R. L., Laney C. D., Madore B. F., Marcella Marconi, Martin W. L., Pel J. W., Petersen J. O., Sandage A., Sasselov, Simon N. R., Stobie R. S., Szabados L., van Genderen A. M., van Genderen A. M., Vittorio Castellani   +32 more
core   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Theoretical models that can be applied to address therapeutic adherence.

Mexican Journal of Medical Research ICSA
Therapeutic adherence is defined by the WHO as "the degree to which patients' behavior, in relation to taking medication, following a diet or making lifestyle changes, corresponds to the recommendations agreed with the healthcare professional." Good ...
Ariana Jiménez Melo
doaj   +1 more source

Theoretical models for duct acoustic propagation and radiation [PDF]

The development of computational methods in acoustics has led to the introduction of analysis and design procedures which model the turbofan inlet as a coupled system, simultaneously modeling propagation and radiation in the presence of realistic ...
Eversman, Walter
core   +1 more source

Optical linear polarization in ultra cool dwarfs: A tool to probe dust in the ultra cool dwarf atmospheres

, 2009
Aims.Recent studies have detected linear polarization in L dwarfs in the optical I band. Theoretical models have been developed to explain this polarization. These models predict higher polarization at shorter wavelengths.
Ackerman, Allard, Bailer-Jones, Basri, Berger, Burrows, Burrows, Burrows, Chabrier, Chandrasekhar, Chiu, Cooper, Cruz, E. L. Martín, Goldman, Golimowski, H. Bouy, Helling, Helling, Kirkpatrick, Knapp, M. R. Zapatero Osorio, Marley, Ménard, N. Phan-Bao, Patten, R. Tata, Reid, Reiners, S. Sengupta, Schmidt, Sengupta, Sengupta, Sengupta, Tsuji, Tsuji, Tsuji, Woitke, Woitke, Zapatero Osorio   +39 more
core   +1 more source

Capital or income breeding? A theoretical model of female reproductive strategies [PDF]

, 2006
Alasdair I. Houston, Philip A. Stephens, Ian L. Boyd, Karin C. Hårding, John M. McNamara   +4 more
openalex   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

A critical analysis of information society conceptualizations from an STS point of view

tripleC: Communication, Capitalism & Critique, 2010
Science and Technology Studies (STS) have developed over the last four decades very rich and deep analysis of the interaction between science, technology and society.
Eduard Aibar
doaj   +1 more source