Results 131 to 140 of about 20,256,945 (318)

Traditional Chinese medicine in the era of immune checkpoint inhibitor: theory, development, and future directions. [PDF]

open access: yesChin Med, 2023
Yu YX   +8 more
europepmc   +1 more source

Towards the Development of a Taxonomic Theory.

open access: yes, 2020
Developing IS theories has been an important goal for many IS researchers. Towards that end, we discuss how taxonomic theory can be developed. According to Gregor, taxonomic theories are theories for analyzing, which she classifies as Type I Theory. More specifically, we show that some taxonomies, after meeting some conditions, can lead to taxonomic ...
Varshney, Upkar   +2 more
openaire   +3 more sources

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

Advancing Behavioral Intervention and Theory Development for Mobile Health: The HeartSteps II Protocol. [PDF]

open access: yesInt J Environ Res Public Health, 2022
Spruijt-Metz D   +12 more
europepmc   +1 more source

IDB News: Vol. 2, no. 5, June 1975

open access: yes, 1975
IDB News is a monthly publication of the Inter-American Development Bank and appears in English and Spanish ...
Inter-American Development Bank
core   +1 more source

The ubiquitin system in normal and infected germinal center B cells

open access: yesFEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis   +2 more
wiley   +1 more source

IDB News: Vol. 1, no. 8, September 1974

open access: yes, 1974
IDB News is a monthly publication of the Inter-American Development Bank and appears in English and Spanish ...
Inter-American Development Bank
core   +1 more source

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