Results 71 to 80 of about 6,774,858 (301)
Mapping the evolution of mitochondrial complex I through structural variation
FEBS Letters, EarlyView.Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Hyman Minsky's Theory of Capitalist Development [PDF]
During the last decade of his life, Hyman Minsky drew on insights acquired from Joseph Schumpeter in an effort to explore the long-term development of capitalism.
Charles J. Whalen
core
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Will Evers and Lakomski be able to find leadership’s Holy Grail?
KEDI Journal of Educational Policy, 2012 In this paper I intend to have a critical look at the theory development issues in the field of educational administration and leadership with a special emphasis on Colin Evers and Gabriel Lakomski’s naturalistic direction.
Kadir Beycioglu
doaj +1 more source
The gulf between rhetoric & reality : an examination of the gap between development theory and development practice in the care of Cambodian orphans : a thesis presented in partial fulfilment of the requirements for the degree of Master of Philosophy in Development Studies at Massey University, Palmerston North Campus [PDF]
, 2005 Like many other Developing World countries. Cambodia is in the midst of an orphan crisis. At least 77,000 children have lost their parents to AIDS and many thousands more have been orphaned by civil war. landmines and other tragedies.
Greenfield, Craig
core
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Contemporary HIV/AIDS research: Insights from knowledge management theory
SAHARA-J, 2017 Knowledge management as a field is concerned with the management of knowledge, including the management of knowledge in research processes. Knowledge management theory has the potential to support research into problems such as HIV, antibiotic resistance
Chris William Callaghan
doaj +1 more source
Constructing a Theory of Educational Administration [PDF]
, 2018 The development of administrative theory has long been a quest for scholars in the field of educational administration. The beginnings of the development of a theory of educational administration began with Griffiths‘ (1959) now classic Administrative ...
Beach, Don M.
core +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source